Gene detail

CDIF104450_RS05180

Histidine kinase, Classic

Clostridioides difficile · GCF_025135955

ClassHKTypeClassicLength248 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_025135955#CDIF104450_RS05180Stable P2CS identifier used across views.
GenomeGCF_025135955Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1504248Run 6 · 565 sequences · id 100% · cov 80%
External referencesWP_021366423.1 · MIST4 CDIF104450_RS05180RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length248 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage160 / 248 aa (64.5%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa248 aa
HisKA: 42-100 aa (59 aa)1HATPase_c: 148-248 aa (101 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
42-100 aa · 59 aa · 23.8% of protein
Raw tokenHisKA:42:2.58e-18:100:59:64
2 HATPase_c#2
148-248 aa · 101 aa · 40.7% of protein
Raw tokenHATPase_c:148:1.8e-28:248:106:109
  • Raw architecture: HisKA:42:2.58e-18:100:59:64#HATPase_c:148:1.8e-28:248:106:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_025135955::NZ_CP021445.1::G00015
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1066444-1067190Genomic interval covered by the local TCS group.
Context group IDGCF_025135955::NZ_CP021445.1::G00015
Context members
CDIF104450_RS05180
Partner locus tags
CDIF104450_RS05180
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021366423.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDIF104450_RS05180Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CP021445.1Sequence record reported by the local genomic context database.
Genomic interval1 066 444-1 067 190 nt747 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 066 444-1 067 190 ntGCF_025135955::NZ_CP021445.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025135955::NZ_CP021445.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP021445.1All displayed genes belong to this local TCS context.
Neighborhood span1 066 444-1 067 190 nt747 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 066 444 nt1 067 190 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1504248Run 6 · HK · 565 sequences
Representative sequenceGCF_000009205#CD630_RS05670Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1504248

Simplified PFAM architecture for HKOC_1504248

PFAM domain coverage: 161 / 495 aa (32.5%)

1 aa495 aa
HisKA: 287-347 aaHisKAHATPase_c: 395-494 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[287-347] | HATPase_c[395-494]
  • Domain count: 2
  • Matched identifier: HKOC_1504248
  • Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS05670

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025135955
AssemblyASM2513595v1 · Complete Genomehaploid
Genome composition4 270 750 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key