Gene detail

NE474_RS15375

Histidine kinase, Classic

Anaerostipes hadrus · GCF_024462215

ClassHKTypeClassicLength452 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024462215#NE474_RS15375Stable P2CS identifier used across views.
GenomeGCF_024462215Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Selected clusterHKOC_1937169Run 6 · 45 sequences · id 100% · cov 80%
External referencesWP_008393291.1 · D4MW63 · MIST4 NE474_RS15375RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likeHisKAHATPase_c
Protein length452 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage279 / 452 aa (61.7%)Merged over positioned domains only.
Domain description1 sCache_like,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa452 aa
sCache_like: 34-132 aa (99 aa)1HisKA: 226-292 aa (67 aa)2HATPase_c: 336-448 aa (113 aa)3
Domain-by-domain annotation3 items
1 sCache_like#1
34-132 aa · 99 aa · 21.9% of protein
Raw tokensCache_like:34:0.000000075:132:105:114
2 HisKA#2
226-292 aa · 67 aa · 14.8% of protein
Raw tokenHisKA:226:5.74e-17:292:67:64
3 HATPase_c#3
336-448 aa · 113 aa · 25.0% of protein
Raw tokenHATPase_c:336:1.22e-29:448:113:109
  • Raw architecture: sCache_like:34:0.000000075:132:105:114#HisKA:226:5.74e-17:292:67:64#HATPase_c:336:1.22e-29:448:113:109
  • Domain description: 1 sCache_like,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024462215::NZ_JANGBA010000066.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span95-2130Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE474_15415RefSeq proteinWP_008393291.1
Context group IDGCF_024462215::NZ_JANGBA010000066.1::G00028
Context members
NE474_RS15375NE474_RS15380
Partner locus tags
NE474_RS15375NE474_RS15380
Partner old locus tags
NE474_15415NE474_15420
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_008393291.1Primary protein accession used for annex mappings.
UniProt accessionD4MW63Primary UniProt accession resolved in the annex database.
UniProt IDD4MW63_ANAHADisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE474_RS15375Primary locus identifier stored in the genes table.
Old locus tagNE474_15415Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANGBA010000066.1Sequence record reported by the local genomic context database.
Genomic interval95-1 453 nt1 359 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span95-2 130 ntGCF_024462215::NZ_JANGBA010000066.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024462215::NZ_JANGBA010000066.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANGBA010000066.1All displayed genes belong to this local TCS context.
Neighborhood span95-2 130 nt2 036 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
95 nt2 130 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE474_RS15380GCF_024462215#NE474_RS15380
RROmpR

1 450-2 130 nt · Reverse (-)

Old locus NE474_15420RefSeq WP_008393290.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1937169Run 6 · HK · 45 sequences
Representative sequenceGCF_000210695#CL2_RS13775Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1937169

Simplified PFAM architecture for HKOC_1937169

PFAM domain coverage: 175 / 452 aa (38.7%)

1 aa452 aa
HisKA: 226-291 aaHisKAHATPase_c: 339-447 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[226-291] | HATPase_c[339-447]
  • Domain count: 2
  • Matched identifier: HKOC_1937169
  • Positioned domains: HisKA 226-291 ; HATPase_c 339-447
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210695#CL2_RS13775

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 649 756 · GCF_024462215
AssemblyASM2446221v1 · Contighaploid
Genome composition3 335 092 bp · 37,0% GCAnaerostipes hadrus
Signal transduction countsGenes 57 · HK 28 · RR 28CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes

Related genes

Preview from the same derived genome key