Gene detail

NE474_RS09115

Histidine kinase, Classic

Anaerostipes hadrus · GCF_024462215

ClassHKTypeClassicLength460 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024462215#NE474_RS09115Stable P2CS identifier used across views.
GenomeGCF_024462215Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Selected clusterHKOC_1833750Run 6 · 39 sequences · id 100% · cov 80%
External referencesWP_008392899.1 · A0A174RGG7 · MIST4 NE474_RS09115RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length460 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 460 aa (53.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa460 aa
HAMP: 162-229 aa (68 aa)1HisKA: 233-299 aa (67 aa)2HATPase_c: 347-457 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
162-229 aa · 68 aa · 14.8% of protein
Raw tokenHAMP:162:0.0000693:229:68:69
2 HisKA#2
233-299 aa · 67 aa · 14.6% of protein
Raw tokenHisKA:233:0.00000000000547:299:67:64
3 HATPase_c#3
347-457 aa · 111 aa · 24.1% of protein
Raw tokenHATPase_c:347:1.32e-29:457:111:109
  • Raw architecture: HAMP:162:0.0000693:229:68:69#HisKA:233:0.00000000000547:299:67:64#HATPase_c:347:1.32e-29:457:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024462215::NZ_JANGBA010000022.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span7439-9557Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE474_09135RefSeq proteinWP_008392899.1
Context group IDGCF_024462215::NZ_JANGBA010000022.1::G00011
Context members
NE474_RS09110NE474_RS09115
Partner locus tags
NE474_RS09110NE474_RS09115
Partner old locus tags
NE474_09130NE474_09135
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_008392899.1Primary protein accession used for annex mappings.
UniProt accessionA0A174RGG7Primary UniProt accession resolved in the annex database.
UniProt IDA0A174RGG7_ANAHADisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE474_RS09115Primary locus identifier stored in the genes table.
Old locus tagNE474_09135Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANGBA010000022.1Sequence record reported by the local genomic context database.
Genomic interval8 157-9 557 nt1 401 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span7 439-9 557 ntGCF_024462215::NZ_JANGBA010000022.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024462215::NZ_JANGBA010000022.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANGBA010000022.1All displayed genes belong to this local TCS context.
Neighborhood span7 439-9 557 nt2 119 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
7 439 nt9 557 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE474_RS09110GCF_024462215#NE474_RS09110
RROmpR

7 439-8 128 nt · Forward (+)

Old locus NE474_09130RefSeq WP_008392900.1
NE474_RS09115GCF_024462215#NE474_RS09115
HKClassicCurrent focus

8 157-9 557 nt · Forward (+)

Old locus NE474_09135RefSeq WP_008392899.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1833750Run 6 · HK · 39 sequences
Representative sequenceGCF_000210695#CL2_RS01900Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1833750

Simplified PFAM architecture for HKOC_1833750

PFAM domain coverage: 178 / 460 aa (38.7%)

1 aa460 aa
HisKA: 233-299 aaHisKAHATPase_c: 347-457 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[233-299] | HATPase_c[347-457]
  • Domain count: 2
  • Matched identifier: HKOC_1833750
  • Positioned domains: HisKA 233-299 ; HATPase_c 347-457
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210695#CL2_RS01900

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 649 756 · GCF_024462215
AssemblyASM2446221v1 · Contighaploid
Genome composition3 335 092 bp · 37,0% GCAnaerostipes hadrus
Signal transduction countsGenes 57 · HK 28 · RR 28CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes

Related genes

Preview from the same derived genome key