1 GAF_3#1
291-411 aa · 121 aa · 18.4% of protein
Raw token
GAF_3:291:0.00000646:411:126:129P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NE474_RS06750
Histidine kinase, Classic
Anaerostipes hadrus · GCF_024462215
ClassHKTypeClassicLength658 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024462215#NE474_RS06750Stable P2CS identifier used across views.
GenomeGCF_024462215Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Domain signature
Compact overview inferred from the domain field
GAF_3HisKAHATPase_c
Protein length658 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage302 / 658 aa (45.9%)Merged over positioned domains only.
Domain description1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa658 aa
Domain-by-domain annotation3 items
2 HisKA#2
431-498 aa · 68 aa · 10.3% of protein
Raw token
HisKA:431:0.00000000000196:498:68:643 HATPase_c#3
541-653 aa · 113 aa · 17.2% of protein
Raw token
HATPase_c:541:6.35e-28:653:113:109- Raw architecture: GAF_3:291:0.00000646:411:126:129#HisKA:431:0.00000000000196:498:68:64#HATPase_c:541:6.35e-28:653:113:109
- Domain description: 1 GAF_3,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_024462215::NZ_JANGBA010000013.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span57951-60618Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE474_06765RefSeq proteinWP_226797265.1
Context group ID
GCF_024462215::NZ_JANGBA010000013.1::G00004Context members
NE474_RS06750NE474_RS06755
Partner locus tags
NE474_RS06750NE474_RS06755
Partner old locus tags
NE474_06765NE474_06770
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_226797265.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNE474_RS06750Primary locus identifier stored in the genes table.
Old locus tagNE474_06765Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANGBA010000013.1Sequence record reported by the local genomic context database.
Genomic interval57 951-59 927 nt1 977 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span57 951-60 618 ntGCF_024462215::NZ_JANGBA010000013.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024462215::NZ_JANGBA010000013.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANGBA010000013.1All displayed genes belong to this local TCS context.
Neighborhood span57 951-60 618 nt2 668 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
57 951 nt60 618 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NE474_RS06750GCF_024462215#NE474_RS06750
HKClassicCurrent focus
57 951-59 927 nt · Forward (+)
NE474_RS06755GCF_024462215#NE474_RS06755
RROmpR
59 920-60 618 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_020538085#LIP56_RS12810Use this link to inspect the representative gene detail.
PFAM architectureDUF4118 + GAF_3 + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0877645
Simplified PFAM architecture for HKOC_0877645
PFAM domain coverage: 407 / 658 aa (61.9%)
1 aa658 aa
DUF4118GAF_3HisKAHATPase_c
- Simplified architecture: DUF4118 + GAF_3 + HisKA + HATPase_c
- Raw architecture: DUF4118[162-268] | GAF_3[291-411] | HisKA[431-498] | HATPase_c[542-652]
- Domain count: 4
- Matched identifier: HKOC_0877645
- Positioned domains: DUF4118 162-268 ; GAF_3 291-411 ; HisKA 431-498 ; HATPase_c 542-652
Cluster members and taxonomy
Representative gene: GCF_020538085#LIP56_RS12810
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 649 756 · GCF_024462215
AssemblyASM2446221v1 · Contighaploid
Genome composition3 335 092 bp · 37,0% GCAnaerostipes hadrus
Signal transduction countsGenes 57 · HK 28 · RR 28CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes
Related genes
Preview from the same derived genome key