Gene detail

NE474_RS00850

Histidine kinase, Hybrid

Anaerostipes hadrus · GCF_024462215

ClassHKTypeHybridLength982 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_024462215#NE474_RS00850Stable P2CS identifier used across views.
GenomeGCF_024462215Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Selected clusterHKOC_0305318Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_256158144.1 · MIST4 NE474_RS00850RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3HisKAHATPase_cResponse_reg
Protein length982 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage487 / 982 aa (49.6%)Merged over positioned domains only.
Domain description1 PAS_3,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa982 aa
PAS_3: 360-429 aa (70 aa)1HisKA: 470-536 aa (67 aa)2HATPase_c: 584-701 aa (118 aa)3Response_reg: 720-833 aa (114 aa)4Response_reg: 861-978 aa (118 aa)5
Domain-by-domain annotation5 items
1 PAS_3#1
360-429 aa · 70 aa · 7.1% of protein
Raw tokenPAS_3:360:0.000042:429:72:89
2 HisKA#2
470-536 aa · 67 aa · 6.8% of protein
Raw tokenHisKA:470:1.67e-18:536:67:64
3 HATPase_c#3
584-701 aa · 118 aa · 12.0% of protein
Raw tokenHATPase_c:584:3.84e-30:701:118:109
4 Response_reg#4
720-833 aa · 114 aa · 11.6% of protein
Raw tokenResponse_reg:720:7.58e-20:833:114:111
5 Response_reg#5
861-978 aa · 118 aa · 12.0% of protein
Raw tokenResponse_reg:861:1.03e-30:978:118:111
  • Raw architecture: PAS_3:360:0.000042:429:72:89#HisKA:470:1.67e-18:536:67:64#HATPase_c:584:3.84e-30:701:118:109#Response_reg:720:7.58e-20:833:114:111#Response_reg:861:1.03e-30:978:118:111
  • Domain description: 1 PAS_3,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_024462215::NZ_JANGBA010000002.1::G00009
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span6928-9876Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE474_00850RefSeq proteinWP_256158144.1
Context group IDGCF_024462215::NZ_JANGBA010000002.1::G00009
Context members
NE474_RS00850
Partner locus tags
NE474_RS00850
Partner old locus tags
NE474_00850
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_256158144.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE474_RS00850Primary locus identifier stored in the genes table.
Old locus tagNE474_00850Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANGBA010000002.1Sequence record reported by the local genomic context database.
Genomic interval6 928-9 876 nt2 949 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span6 928-9 876 ntGCF_024462215::NZ_JANGBA010000002.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024462215::NZ_JANGBA010000002.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANGBA010000002.1All displayed genes belong to this local TCS context.
Neighborhood span6 928-9 876 nt2 949 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 928 nt9 876 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

NE474_RS00850GCF_024462215#NE474_RS00850
HKHybridCurrent focus

6 928-9 876 nt · Reverse (-)

Old locus NE474_00850RefSeq WP_256158144.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0305318Run 6 · HK · 1 sequences
Representative sequenceGCF_024462215#NE474_RS00850The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0305318

Simplified PFAM architecture for HKOC_0305318

PFAM domain coverage: 414 / 982 aa (42.2%)

1 aa982 aa
HisKA: 470-536 aaHisKAHATPase_c: 584-700 aaHATPase_cResponse_reg: 720-832 aaResponse_regResponse_reg: 861-977 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[470-536] | HATPase_c[584-700] | Response_reg[720-832] | Response_reg[861-977]
  • Domain count: 4
  • Matched identifier: HKOC_0305318
  • Positioned domains: HisKA 470-536 ; HATPase_c 584-700 ; Response_reg 720-832 ; Response_reg 861-977
Cluster members and taxonomy
Visualization

Representative gene: GCF_024462215#NE474_RS00850

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 649 756 · GCF_024462215
AssemblyASM2446221v1 · Contighaploid
Genome composition3 335 092 bp · 37,0% GCAnaerostipes hadrus
Signal transduction countsGenes 57 · HK 28 · RR 28CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes

Related genes

Preview from the same derived genome key