Gene detail

NE474_RS00610

Histidine kinase, Classic

Anaerostipes hadrus · GCF_024462215

ClassHKTypeClassicLength488 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024462215#NE474_RS00610Stable P2CS identifier used across views.
GenomeGCF_024462215Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Selected clusterHKOC_1554315Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_256158136.1 · MIST4 NE474_RS00610RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length488 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage257 / 488 aa (52.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa488 aa
HAMP: 191-263 aa (73 aa)1His_kinase: 279-355 aa (77 aa)2HATPase_c: 377-483 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
191-263 aa · 73 aa · 15.0% of protein
Raw tokenHAMP:191:0.00000000208:263:73:69
2 His_kinase#2
279-355 aa · 77 aa · 15.8% of protein
Raw tokenHis_kinase:279:1.02e-35:355:77:80
3 HATPase_c#3
377-483 aa · 107 aa · 21.9% of protein
Raw tokenHATPase_c:377:0.0000000000000597:483:108:109
  • Raw architecture: HAMP:191:0.00000000208:263:73:69#His_kinase:279:1.02e-35:355:77:80#HATPase_c:377:0.0000000000000597:483:108:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024462215::NZ_JANGBA010000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span145110-148195Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE474_00610RefSeq proteinWP_256158136.1
Context group IDGCF_024462215::NZ_JANGBA010000001.1::G00002
Context members
NE474_RS00610NE474_RS00615
Partner locus tags
NE474_RS00610NE474_RS00615
Partner old locus tags
NE474_00610NE474_00615
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_256158136.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE474_RS00610Primary locus identifier stored in the genes table.
Old locus tagNE474_00610Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANGBA010000001.1Sequence record reported by the local genomic context database.
Genomic interval145 110-146 576 nt1 467 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span145 110-148 195 ntGCF_024462215::NZ_JANGBA010000001.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024462215::NZ_JANGBA010000001.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANGBA010000001.1All displayed genes belong to this local TCS context.
Neighborhood span145 110-148 195 nt3 086 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
145 110 nt148 195 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE474_RS00610GCF_024462215#NE474_RS00610
HKClassicCurrent focus

145 110-146 576 nt · Reverse (-)

Old locus NE474_00610RefSeq WP_256158136.1
NE474_RS00615GCF_024462215#NE474_RS00615
RRunclassified

146 576-148 195 nt · Reverse (-)

Old locus NE474_00615RefSeq WP_256158137.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1554315Run 6 · HK · 2 sequences
Representative sequenceGCF_024462215#NE474_RS00610The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1554315

Simplified PFAM architecture for HKOC_1554315

PFAM domain coverage: 236 / 488 aa (48.4%)

1 aa488 aa
HAMP: 211-262 aaHAMPHis_kinase: 279-355 aaHis_kinaseHATPase_c: 376-482 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[211-262] | His_kinase[279-355] | HATPase_c[376-482]
  • Domain count: 3
  • Matched identifier: HKOC_1554315
  • Positioned domains: HAMP 211-262 ; His_kinase 279-355 ; HATPase_c 376-482
Cluster members and taxonomy
Visualization

Representative gene: GCF_024462215#NE474_RS00610

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 649 756 · GCF_024462215
AssemblyASM2446221v1 · Contighaploid
Genome composition3 335 092 bp · 37,0% GCAnaerostipes hadrus
Signal transduction countsGenes 57 · HK 28 · RR 28CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes

Related genes

Preview from the same derived genome key