Gene detail

NE621_RS09805

Histidine kinase, Classic

Agathobacter rectalis · GCF_024461635

ClassHKTypeClassicLength597 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024461635#NE621_RS09805Stable P2CS identifier used across views.
GenomeGCF_024461635Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Agathobacter
Selected clusterHKOC_1071218Run 6 · 3 sequences · id 100% · cov 80%
External referencesWP_306780953.1 · A0AAW4UFE2 · MIST4 NE621_RS09805RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length597 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage262 / 597 aa (43.9%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa597 aa
HAMP: 288-357 aa (70 aa)1His_kinase: 372-448 aa (77 aa)2HATPase_c: 463-577 aa (115 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
288-357 aa · 70 aa · 11.7% of protein
Raw tokenHAMP:288:0.000000586:357:70:69
2 His_kinase#2
372-448 aa · 77 aa · 12.9% of protein
Raw tokenHis_kinase:372:1.83e-25:448:77:80
3 HATPase_c#3
463-577 aa · 115 aa · 19.3% of protein
Raw tokenHATPase_c:463:0.00000000000000347:577:115:109
  • Raw architecture: HAMP:288:0.000000586:357:70:69#His_kinase:372:1.83e-25:448:77:80#HATPase_c:463:0.00000000000000347:577:115:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024461635::NZ_JANFZZ010000012.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span14105-16905Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE621_09825RefSeq proteinWP_306780953.1
Context group IDGCF_024461635::NZ_JANFZZ010000012.1::G00009
Context members
NE621_RS09800NE621_RS09805
Partner locus tags
NE621_RS09800NE621_RS09805
Partner old locus tags
NE621_09820NE621_09825
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_306780953.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW4UFE2Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW4UFE2_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE621_RS09805Primary locus identifier stored in the genes table.
Old locus tagNE621_09825Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZZ010000012.1Sequence record reported by the local genomic context database.
Genomic interval15 112-16 905 nt1 794 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span14 105-16 905 ntGCF_024461635::NZ_JANFZZ010000012.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024461635::NZ_JANFZZ010000012.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZZ010000012.1All displayed genes belong to this local TCS context.
Neighborhood span14 105-16 905 nt2 801 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
14 105 nt16 905 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE621_RS09800GCF_024461635#NE621_RS09800
RRunclassified

14 105-15 115 nt · Reverse (-)

Old locus NE621_09820RefSeq WP_012743643.1
NE621_RS09805GCF_024461635#NE621_RS09805
HKClassicCurrent focus

15 112-16 905 nt · Reverse (-)

Old locus NE621_09825RefSeq WP_306780953.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1071218Run 6 · HK · 3 sequences
Representative sequenceGCF_020557395#LIZ56_RS10340Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1071218

Simplified PFAM architecture for HKOC_1071218

PFAM domain coverage: 188 / 597 aa (31.5%)

1 aa597 aa
His_kinase: 373-448 aaHis_kinaseHATPase_c: 465-576 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[373-448] | HATPase_c[465-576]
  • Domain count: 2
  • Matched identifier: HKOC_1071218
  • Positioned domains: His_kinase 373-448 ; HATPase_c 465-576
Cluster members and taxonomy
Visualization

Representative gene: GCF_020557395#LIZ56_RS10340

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 491 · GCF_024461635
AssemblyASM2446163v1 · Contighaploid
Genome composition3 406 890 bp · 41,0% GCAgathobacter rectalis
Signal transduction countsGenes 92 · HK 37 · RR 52CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAgathobacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Agathobacter

Related genes

Preview from the same derived genome key