Gene detail

NE621_RS07210

Histidine kinase, CheA

Agathobacter rectalis · GCF_024461635

ClassHKTypeCheALength706 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024461635#NE621_RS07210Stable P2CS identifier used across views.
GenomeGCF_024461635Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Agathobacter
Selected clusterHKOC_0758201Run 6 · 7 sequences · id 100% · cov 80%
External referencesWP_306771120.1 · A0AAW4UEE8 · MIST4 NE621_RS07210RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HptH-kinase_dimHATPase_cCheW
Protein length706 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage426 / 706 aa (60.3%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa706 aa
Hpt: 5-98 aa (94 aa)1H-kinase_dim: 324-387 aa (64 aa)2HATPase_c: 435-574 aa (140 aa)3CheW: 579-706 aa (128 aa)4
Domain-by-domain annotation4 items
1 Hpt#1
5-98 aa · 94 aa · 13.3% of protein
Raw tokenHpt:5:1.93e-17:98:94:84
2 H-kinase_dim#2
324-387 aa · 64 aa · 9.1% of protein
Raw tokenH-kinase_dim:324:0.00000000000000115:387:67:67
3 HATPase_c#3
435-574 aa · 140 aa · 19.8% of protein
Raw tokenHATPase_c:435:4.09e-16:574:140:109
4 CheW#4
579-706 aa · 128 aa · 18.1% of protein
Raw tokenCheW:579:2.47e-30:706:135:138
  • Raw architecture: Hpt:5:1.93e-17:98:94:84#H-kinase_dim:324:0.00000000000000115:387:67:67#HATPase_c:435:4.09e-16:574:140:109#CheW:579:2.47e-30:706:135:138
  • Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024461635::NZ_JANFZZ010000007.1::G00048
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span77959-81142Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE621_07225RefSeq proteinWP_306771120.1
Context group IDGCF_024461635::NZ_JANFZZ010000007.1::G00048
Context members
NE621_RS07210NE621_RS07215
Partner locus tags
NE621_RS07210NE621_RS07215
Partner old locus tags
NE621_07225NE621_07230
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_306771120.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW4UEE8Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW4UEE8_9FIRMDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE621_RS07210Primary locus identifier stored in the genes table.
Old locus tagNE621_07225Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZZ010000007.1Sequence record reported by the local genomic context database.
Genomic interval77 959-80 079 nt2 121 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span77 959-81 142 ntGCF_024461635::NZ_JANFZZ010000007.1::G00048

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024461635::NZ_JANFZZ010000007.1::G00048

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZZ010000007.1All displayed genes belong to this local TCS context.
Neighborhood span77 959-81 142 nt3 184 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
77 959 nt81 142 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE621_RS07210GCF_024461635#NE621_RS07210
HKCheACurrent focus

77 959-80 079 nt · Reverse (-)

Old locus NE621_07225RefSeq WP_306771120.1
NE621_RS07215GCF_024461635#NE621_RS07215
RRCheB

80 081-81 142 nt · Reverse (-)

Old locus NE621_07230RefSeq WP_306780785.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0758201Run 6 · HK · 7 sequences
Representative sequenceGCF_014866295#RDJ68_RS00745Use this link to inspect the representative gene detail.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0758201

Simplified PFAM architecture for HKOC_0758201

PFAM domain coverage: 502 / 706 aa (71.1%)

1 aa706 aa
Hpt: 5-97 aaHptP2: 183-260 aaP2H-kinase_dim: 323-387 aaH-kinase_dimHATPase_c: 436-574 aaHATPase_cCheW: 579-705 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[5-97] | P2[183-260] | H-kinase_dim[323-387] | HATPase_c[436-574] | CheW[579-705]
  • Domain count: 5
  • Matched identifier: HKOC_0758201
  • Positioned domains: Hpt 5-97 ; P2 183-260 ; H-kinase_dim 323-387 ; HATPase_c 436-574 ; CheW 579-705
Cluster members and taxonomy
Visualization

Representative gene: GCF_014866295#RDJ68_RS00745

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 491 · GCF_024461635
AssemblyASM2446163v1 · Contighaploid
Genome composition3 406 890 bp · 41,0% GCAgathobacter rectalis
Signal transduction countsGenes 92 · HK 37 · RR 52CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAgathobacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Agathobacter

Related genes

Preview from the same derived genome key