Gene detail

NE621_RS05435

Histidine kinase, Classic

Agathobacter rectalis · GCF_024461635

ClassHKTypeClassicLength597 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024461635#NE621_RS05435Stable P2CS identifier used across views.
GenomeGCF_024461635Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Agathobacter
Selected clusterHKOC_1068587Run 6 · 6 sequences · id 100% · cov 80%
External referencesWP_012741390.1 · C4ZBY3 · MIST4 NE621_RS05435RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1His_kinaseHATPase_c
Protein length597 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage383 / 597 aa (64.2%)Merged over positioned domains only.
Domain description1 dCache_1,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa597 aa
dCache_1: 82-277 aa (196 aa)1His_kinase: 379-458 aa (80 aa)2HATPase_c: 473-579 aa (107 aa)3
Domain-by-domain annotation3 items
1 dCache_1#1
82-277 aa · 196 aa · 32.8% of protein
Raw tokendCache_1:82:0.000000000019:277:204:195
2 His_kinase#2
379-458 aa · 80 aa · 13.4% of protein
Raw tokenHis_kinase:379:1.82e-34:458:80:80
3 HATPase_c#3
473-579 aa · 107 aa · 17.9% of protein
Raw tokenHATPase_c:473:2.66e-16:579:110:109
  • Raw architecture: dCache_1:82:0.000000000019:277:204:195#His_kinase:379:1.82e-34:458:80:80#HATPase_c:473:2.66e-16:579:110:109
  • Domain description: 1 dCache_1,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024461635::NZ_JANFZZ010000005.1::G00043
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span45107-48485Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE621_05450RefSeq proteinWP_012741390.1
Context group IDGCF_024461635::NZ_JANFZZ010000005.1::G00043
Context members
NE621_RS05435NE621_RS05440
Partner locus tags
NE621_RS05435NE621_RS05440
Partner old locus tags
NE621_05450NE621_05455
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_012741390.1Primary protein accession used for annex mappings.
UniProt accessionC4ZBY3Primary UniProt accession resolved in the annex database.
UniProt IDC4ZBY3_AGARVDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE621_RS05435Primary locus identifier stored in the genes table.
Old locus tagNE621_05450Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZZ010000005.1Sequence record reported by the local genomic context database.
Genomic interval45 107-46 900 nt1 794 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span45 107-48 485 ntGCF_024461635::NZ_JANFZZ010000005.1::G00043

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024461635::NZ_JANFZZ010000005.1::G00043

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZZ010000005.1All displayed genes belong to this local TCS context.
Neighborhood span45 107-48 485 nt3 379 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
45 107 nt48 485 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE621_RS05435GCF_024461635#NE621_RS05435
HKClassicCurrent focus

45 107-46 900 nt · Reverse (-)

Old locus NE621_05450RefSeq WP_012741390.1
NE621_RS05440GCF_024461635#NE621_RS05440
RRunclassified

46 881-48 485 nt · Reverse (-)

Old locus NE621_05455RefSeq WP_118141963.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1068587Run 6 · HK · 6 sequences
Representative sequenceGCF_000020605#EUBREC_RS02175Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1068587

Simplified PFAM architecture for HKOC_1068587

PFAM domain coverage: 421 / 597 aa (70.5%)

1 aa597 aa
dCache_1: 41-277 aadCache_1His_kinase: 380-458 aaHis_kinaseHATPase_c: 475-579 aaHATPase_c
dCache_1His_kinaseHATPase_c
  • Simplified architecture: dCache_1 + His_kinase + HATPase_c
  • Raw architecture: dCache_1[41-277] | His_kinase[380-458] | HATPase_c[475-579]
  • Domain count: 3
  • Matched identifier: HKOC_1068587
  • Positioned domains: dCache_1 41-277 ; His_kinase 380-458 ; HATPase_c 475-579
Cluster members and taxonomy
Visualization

Representative gene: GCF_000020605#EUBREC_RS02175

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 491 · GCF_024461635
AssemblyASM2446163v1 · Contighaploid
Genome composition3 406 890 bp · 41,0% GCAgathobacter rectalis
Signal transduction countsGenes 92 · HK 37 · RR 52CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAgathobacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Agathobacter

Related genes

Preview from the same derived genome key