Gene detail

NE621_RS03490

Histidine kinase, Classic

Agathobacter rectalis · GCF_024461635

ClassHKTypeClassicLength385 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024461635#NE621_RS03490Stable P2CS identifier used across views.
GenomeGCF_024461635Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Agathobacter
Selected clusterHKOC_2568426Run 6 · 4 sequences · id 100% · cov 80%
External referencesWP_306780399.1 · A0AAW4UA85 · MIST4 NE621_RS03490RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length385 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 385 aa (64.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa385 aa
HAMP: 89-159 aa (71 aa)1HisKA: 164-230 aa (67 aa)2HATPase_c: 272-380 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
89-159 aa · 71 aa · 18.4% of protein
Raw tokenHAMP:89:0.000000000945:159:71:69
2 HisKA#2
164-230 aa · 67 aa · 17.4% of protein
Raw tokenHisKA:164:0.00000000025:230:67:64
3 HATPase_c#3
272-380 aa · 109 aa · 28.3% of protein
Raw tokenHATPase_c:272:2.75e-31:380:109:109
  • Raw architecture: HAMP:89:0.000000000945:159:71:69#HisKA:164:0.00000000025:230:67:64#HATPase_c:272:2.75e-31:380:109:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024461635::NZ_JANFZZ010000003.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span59718-61552Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE621_03495RefSeq proteinWP_306780399.1
Context group IDGCF_024461635::NZ_JANFZZ010000003.1::G00030
Context members
NE621_RS03485NE621_RS03490
Partner locus tags
NE621_RS03485NE621_RS03490
Partner old locus tags
NE621_03490NE621_03495
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_306780399.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW4UA85Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW4UA85_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE621_RS03490Primary locus identifier stored in the genes table.
Old locus tagNE621_03495Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZZ010000003.1Sequence record reported by the local genomic context database.
Genomic interval60 395-61 552 nt1 158 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span59 718-61 552 ntGCF_024461635::NZ_JANFZZ010000003.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024461635::NZ_JANFZZ010000003.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZZ010000003.1All displayed genes belong to this local TCS context.
Neighborhood span59 718-61 552 nt1 835 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
59 718 nt61 552 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE621_RS03485GCF_024461635#NE621_RS03485
RROmpR

59 718-60 398 nt · Forward (+)

Old locus NE621_03490RefSeq WP_022292389.1
NE621_RS03490GCF_024461635#NE621_RS03490
HKClassicCurrent focus

60 395-61 552 nt · Forward (+)

Old locus NE621_03495RefSeq WP_306780399.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2568426Run 6 · HK · 4 sequences
Representative sequenceGCF_020557395#LIZ56_RS00850Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2568426

Simplified PFAM architecture for HKOC_2568426

PFAM domain coverage: 174 / 385 aa (45.2%)

1 aa385 aa
HisKA: 164-230 aaHisKAHATPase_c: 275-381 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[164-230] | HATPase_c[275-381]
  • Domain count: 2
  • Matched identifier: HKOC_2568426
  • Positioned domains: HisKA 164-230 ; HATPase_c 275-381
Cluster members and taxonomy
Visualization

Representative gene: GCF_020557395#LIZ56_RS00850

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 491 · GCF_024461635
AssemblyASM2446163v1 · Contighaploid
Genome composition3 406 890 bp · 41,0% GCAgathobacter rectalis
Signal transduction countsGenes 92 · HK 37 · RR 52CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAgathobacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Agathobacter

Related genes

Preview from the same derived genome key