Gene detail

NE631_RS09425

Histidine kinase, Unorthodox

Anaerostipes hadrus · GCF_024460575

ClassHKTypeUnorthodoxLength804 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460575#NE631_RS09425Stable P2CS identifier used across views.
GenomeGCF_024460575Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Selected clusterHKOC_0550391Run 6 · 7 sequences · id 100% · cov 80%
External referencesWP_173725866.1 · A0ABX2I0V6 · MIST4 NE631_RS09425RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_regHpt
Protein length804 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage374 / 804 aa (46.5%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_reg,1 HptSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa804 aa
HisKA: 208-273 aa (66 aa)1HATPase_c: 320-433 aa (114 aa)2Response_reg: 462-572 aa (111 aa)3Hpt: 628-710 aa (83 aa)4
Domain-by-domain annotation4 items
1 HisKA#1
208-273 aa · 66 aa · 8.2% of protein
Raw tokenHisKA:208:1.6e-19:273:66:64
2 HATPase_c#2
320-433 aa · 114 aa · 14.2% of protein
Raw tokenHATPase_c:320:1.31e-34:433:114:109
3 Response_reg#3
462-572 aa · 111 aa · 13.8% of protein
Raw tokenResponse_reg:462:3.24e-24:572:111:111
4 Hpt#4
628-710 aa · 83 aa · 10.3% of protein
Raw tokenHpt:628:0.00000000424:710:83:84
  • Raw architecture: HisKA:208:1.6e-19:273:66:64#HATPase_c:320:1.31e-34:433:114:109#Response_reg:462:3.24e-24:572:111:111#Hpt:628:0.00000000424:710:83:84
  • Domain description: 1 HisKA,1 HATPase_c,1 Response_reg,1 Hpt
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024460575::NZ_JANFYQ010000019.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span17663-20685Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE631_09480RefSeq proteinWP_173725866.1
Context group IDGCF_024460575::NZ_JANFYQ010000019.1::G00012
Context members
NE631_RS09425NE631_RS09430
Partner locus tags
NE631_RS09425NE631_RS09430
Partner old locus tags
NE631_09480NE631_09485
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_173725866.1Primary protein accession used for annex mappings.
UniProt accessionA0ABX2I0V6Primary UniProt accession resolved in the annex database.
UniProt IDA0ABX2I0V6_ANAHADisplay identifier provided by UniProt.
GO / PubMed0 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE631_RS09425Primary locus identifier stored in the genes table.
Old locus tagNE631_09480Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFYQ010000019.1Sequence record reported by the local genomic context database.
Genomic interval17 663-20 077 nt2 415 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span17 663-20 685 ntGCF_024460575::NZ_JANFYQ010000019.1::G00012

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460575::NZ_JANFYQ010000019.1::G00012

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFYQ010000019.1All displayed genes belong to this local TCS context.
Neighborhood span17 663-20 685 nt3 023 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
17 663 nt20 685 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE631_RS09425GCF_024460575#NE631_RS09425
HKUnorthodoxCurrent focus

17 663-20 077 nt · Forward (+)

Old locus NE631_09480RefSeq WP_173725866.1
NE631_RS09430GCF_024460575#NE631_RS09430
RRNarL

20 074-20 685 nt · Forward (+)

Old locus NE631_09485RefSeq WP_243872800.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0550391Run 6 · HK · 7 sequences
Representative sequenceGCF_013302455#G4934_RS13695Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c + Response_reg + Hpt4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0550391

Simplified PFAM architecture for HKOC_0550391

PFAM domain coverage: 356 / 804 aa (44.3%)

1 aa804 aa
HisKA: 208-273 aaHisKAHATPase_c: 320-432 aaHATPase_cResponse_reg: 462-570 aaResponse_regHpt: 629-696 aaHpt
HisKAHATPase_cResponse_regHpt
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Hpt
  • Raw architecture: HisKA[208-273] | HATPase_c[320-432] | Response_reg[462-570] | Hpt[629-696]
  • Domain count: 4
  • Matched identifier: HKOC_0550391
  • Positioned domains: HisKA 208-273 ; HATPase_c 320-432 ; Response_reg 462-570 ; Hpt 629-696
Cluster members and taxonomy
Visualization

Representative gene: GCF_013302455#G4934_RS13695

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 649 756 · GCF_024460575
AssemblyASM2446057v1 · Contighaploid
Genome composition3 396 819 bp · 37,0% GCAnaerostipes hadrus
Signal transduction countsGenes 58 · HK 28 · RR 29CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes

Related genes

Preview from the same derived genome key