Gene detail

NE704_RS08140

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_024459975

ClassHKTypeClassicLength651 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024459975#NE704_RS08140Stable P2CS identifier used across views.
GenomeGCF_024459975Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_0894700Run 6 · 15 sequences · id 100% · cov 80%
External referencesWP_101879385.1 · A0A2N5NJI9 · MIST4 NE704_RS08140RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length651 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage359 / 651 aa (55.1%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa651 aa
dCache_1: 208-309 aa (102 aa)1HAMP: 333-402 aa (70 aa)2His_kinase: 424-505 aa (82 aa)3HATPase_c: 524-628 aa (105 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
208-309 aa · 102 aa · 15.7% of protein
Raw tokendCache_1:208:0.0000000232:309:105:195
2 HAMP#2
333-402 aa · 70 aa · 10.8% of protein
Raw tokenHAMP:333:0.0000000000018:402:70:69
3 His_kinase#3
424-505 aa · 82 aa · 12.6% of protein
Raw tokenHis_kinase:424:5.84e-23:505:82:80
4 HATPase_c#4
524-628 aa · 105 aa · 16.1% of protein
Raw tokenHATPase_c:524:0.00000000000365:628:108:109
  • Raw architecture: dCache_1:208:0.0000000232:309:105:195#HAMP:333:0.0000000000018:402:70:69#His_kinase:424:5.84e-23:505:82:80#HATPase_c:524:0.00000000000365:628:108:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024459975::NZ_JANFXP010000010.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span94907-98360Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE704_08170RefSeq proteinWP_101879385.1
Context group IDGCF_024459975::NZ_JANFXP010000010.1::G00007
Context members
NE704_RS08135NE704_RS08140
Partner locus tags
NE704_RS08135NE704_RS08140
Partner old locus tags
NE704_08165NE704_08170
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_101879385.1Primary protein accession used for annex mappings.
UniProt accessionA0A2N5NJI9Primary UniProt accession resolved in the annex database.
UniProt IDA0A2N5NJI9_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE704_RS08140Primary locus identifier stored in the genes table.
Old locus tagNE704_08170Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFXP010000010.1Sequence record reported by the local genomic context database.
Genomic interval96 405-98 360 nt1 956 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span94 907-98 360 ntGCF_024459975::NZ_JANFXP010000010.1::G00007

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024459975::NZ_JANFXP010000010.1::G00007

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFXP010000010.1All displayed genes belong to this local TCS context.
Neighborhood span94 907-98 360 nt3 454 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
94 907 nt98 360 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE704_RS08135GCF_024459975#NE704_RS08135
RRunclassified

94 907-96 430 nt · Reverse (-)

Old locus NE704_08165RefSeq WP_101874745.1
NE704_RS08140GCF_024459975#NE704_RS08140
HKClassicCurrent focus

96 405-98 360 nt · Reverse (-)

Old locus NE704_08170RefSeq WP_101879385.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0894700Run 6 · HK · 15 sequences
Representative sequenceGCF_002865435#CDL22_RS07910Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0894700

Simplified PFAM architecture for HKOC_0894700

PFAM domain coverage: 478 / 651 aa (73.4%)

1 aa651 aa
dCache_1: 70-311 aadCache_1HAMP: 351-400 aaHAMPHis_kinase: 424-504 aaHis_kinaseHATPase_c: 524-628 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[70-311] | HAMP[351-400] | His_kinase[424-504] | HATPase_c[524-628]
  • Domain count: 4
  • Matched identifier: HKOC_0894700
  • Positioned domains: dCache_1 70-311 ; HAMP 351-400 ; His_kinase 424-504 ; HATPase_c 524-628
Cluster members and taxonomy
Visualization

Representative gene: GCF_002865435#CDL22_RS07910

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_024459975
AssemblyASM2445997v1 · Contighaploid
Genome composition3 099 021 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key