1 HAMP#1
166-232 aa · 67 aa · 14.3% of protein
Raw token
HAMP:166:0.00000391:232:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NMF48_RS07485
Histidine kinase, Classic
Clostridioides difficile · GCF_024260465
ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024260465#NMF48_RS07485Stable P2CS identifier used across views.
GenomeGCF_024260465Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 467 aa (51.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
Domain-by-domain annotation3 items
2 HisKA#2
245-312 aa · 68 aa · 14.6% of protein
Raw token
HisKA:245:0.000000000000018:312:68:643 HATPase_c#3
359-465 aa · 107 aa · 22.9% of protein
Raw token
HATPase_c:359:1.07e-26:465:108:109- Raw architecture: HAMP:166:0.00000391:232:69:69#HisKA:245:0.000000000000018:312:68:64#HATPase_c:359:1.07e-26:465:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_024260465::NZ_JANCJZ010000004.1::G00037
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span50005-52137Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNMF48_07515RefSeq proteinWP_254484883.1
Context group ID
GCF_024260465::NZ_JANCJZ010000004.1::G00037Context members
NMF48_RS07480NMF48_RS07485
Partner locus tags
NMF48_RS07480NMF48_RS07485
Partner old locus tags
NMF48_07510NMF48_07515
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_254484883.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNMF48_RS07485Primary locus identifier stored in the genes table.
Old locus tagNMF48_07515Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANCJZ010000004.1Sequence record reported by the local genomic context database.
Genomic interval50 734-52 137 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span50 005-52 137 ntGCF_024260465::NZ_JANCJZ010000004.1::G00037
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024260465::NZ_JANCJZ010000004.1::G00037Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANCJZ010000004.1All displayed genes belong to this local TCS context.
Neighborhood span50 005-52 137 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
50 005 nt52 137 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NMF48_RS07480GCF_024260465#NMF48_RS07480
RROmpR
50 005-50 730 nt · Forward (+)
NMF48_RS07485GCF_024260465#NMF48_RS07485
HKClassicCurrent focus
50 734-52 137 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_024260465#NMF48_RS07485The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1755471
Simplified PFAM architecture for HKOC_1755471
PFAM domain coverage: 172 / 467 aa (36.8%)
1 aa467 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[245-309] | HATPase_c[359-465]
- Domain count: 2
- Matched identifier: HKOC_1755471
- Positioned domains: HisKA 245-309 ; HATPase_c 359-465
Cluster members and taxonomy
Representative gene: GCF_024260465#NMF48_RS07485
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_024260465
AssemblyASM2426046v1 · Contighaploid
Genome composition4 084 231 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key