Gene detail

NMF89_RS04475

Histidine kinase, Classic

Clostridioides difficile · GCF_024260265

ClassHKTypeClassicLength912 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_024260265#NMF89_RS04475Stable P2CS identifier used across views.
GenomeGCF_024260265Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0387889Run 6 · 42 sequences · id 100% · cov 80%
External referencesWP_021375977.1 · MIST4 NMF89_RS04475RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_9HisKAHATPase_c
Protein length912 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage284 / 912 aa (31.1%)Merged over positioned domains only.
Domain description1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa912 aa
PAS_9: 529-629 aa (101 aa)1HisKA: 655-726 aa (72 aa)2HATPase_c: 773-883 aa (111 aa)3
Domain-by-domain annotation3 items
1 PAS_9#1
529-629 aa · 101 aa · 11.1% of protein
Raw tokenPAS_9:529:0.0000762:629:101:102
2 HisKA#2
655-726 aa · 72 aa · 7.9% of protein
Raw tokenHisKA:655:0.00000000000000745:726:72:64
3 HATPase_c#3
773-883 aa · 111 aa · 12.2% of protein
Raw tokenHATPase_c:773:3.52e-31:883:111:109
  • Raw architecture: PAS_9:529:0.0000762:629:101:102#HisKA:655:0.00000000000000745:726:72:64#HATPase_c:773:3.52e-31:883:111:109
  • Domain description: 1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_024260265::NZ_JANCKN010000003.1::G00039
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span243006-245744Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNMF89_04470RefSeq proteinWP_021375977.1
Context group IDGCF_024260265::NZ_JANCKN010000003.1::G00039
Context members
NMF89_RS04475
Partner locus tags
NMF89_RS04475
Partner old locus tags
NMF89_04470
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021375977.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNMF89_RS04475Primary locus identifier stored in the genes table.
Old locus tagNMF89_04470Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANCKN010000003.1Sequence record reported by the local genomic context database.
Genomic interval243 006-245 744 nt2 739 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span243 006-245 744 ntGCF_024260265::NZ_JANCKN010000003.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024260265::NZ_JANCKN010000003.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANCKN010000003.1All displayed genes belong to this local TCS context.
Neighborhood span243 006-245 744 nt2 739 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
243 006 nt245 744 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

NMF89_RS04475GCF_024260265#NMF89_RS04475
HKClassicCurrent focus

243 006-245 744 nt · Forward (+)

Old locus NMF89_04470RefSeq WP_021375977.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0387889Run 6 · HK · 42 sequences
Representative sequenceGCF_000449185#QCW_RS12630Use this link to inspect the representative gene detail.
PFAM architecturePAS_8 + PAS_9 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0387889

Simplified PFAM architecture for HKOC_0387889

PFAM domain coverage: 340 / 912 aa (37.3%)

1 aa912 aa
PAS_8: 303-355 aaPAS_8PAS_9: 529-632 aaPAS_9HisKA: 655-726 aaHisKAHATPase_c: 773-883 aaHATPase_c
PAS_8PAS_9HisKAHATPase_c
  • Simplified architecture: PAS_8 + PAS_9 + HisKA + HATPase_c
  • Raw architecture: PAS_8[303-355] | PAS_9[529-632] | HisKA[655-726] | HATPase_c[773-883]
  • Domain count: 4
  • Matched identifier: HKOC_0387889
  • Positioned domains: PAS_8 303-355 ; PAS_9 529-632 ; HisKA 655-726 ; HATPase_c 773-883
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449185#QCW_RS12630

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 42 over 42 total members. Page 1 / 1.

GCF_000449185#QCW_RS12630 (representative)
QCW_RS12630 · HK · Classic
RefSeq: WP_021375977.1
GCF_000531385#BN169_RS12730
BN169_RS12730 · HK · Classic
RefSeq: WP_021375977.1
GCF_001704755#DCQ03_RS02430
DCQ03_RS02430 · HK · Classic
RefSeq: WP_021375977.1
GCF_001704795#DCQ01_RS02065
DCQ01_RS02065 · HK · Classic
RefSeq: WP_021375977.1
GCF_001704805#DCP99_RS02965
DCP99_RS02965 · HK · Classic
RefSeq: WP_021375977.1
GCF_002165155#DCQ05_RS04370
DCQ05_RS04370 · HK · Classic
RefSeq: WP_021375977.1
GCF_002165175#DCQ02_RS02765
DCQ02_RS02765 · HK · Classic
RefSeq: WP_021375977.1
GCF_002250295#B7359_RS05190
B7359_RS05190 · HK · Classic
RefSeq: WP_021375977.1
GCF_003456975#CDIF102859_RS13885
CDIF102859_RS13885 · HK · Classic
RefSeq: WP_021375977.1
GCF_003457015#CDIF102860_RS14040
CDIF102860_RS14040 · HK · Classic
RefSeq: WP_021375977.1
GCF_003457035#CDIF102978_RS14040
CDIF102978_RS14040 · HK · Classic
RefSeq: WP_021375977.1
GCF_004314505#E0O34_RS08810
E0O34_RS08810 · HK · Classic
RefSeq: WP_021375977.1
GCF_004314745#E0O51_RS11205
E0O51_RS11205 · HK · Classic
RefSeq: WP_021375977.1
GCF_004315765#E0P52_RS11570
E0P52_RS11570 · HK · Classic
RefSeq: WP_021375977.1
GCF_005786645#EDC95_RS03580
EDC95_RS03580 · HK · Classic
RefSeq: WP_021375977.1
GCF_012029905#GSQ35_RS01475
GSQ35_RS01475 · HK · Classic
RefSeq: WP_021375977.1
GCF_012030175#GSQ43_RS02125
GSQ43_RS02125 · HK · Classic
RefSeq: WP_021375977.1
GCF_012955915#HGQ81_RS05610
HGQ81_RS05610 · HK · Classic
RefSeq: WP_021375977.1
GCF_019426665#K1N14_RS06580
K1N14_RS06580 · HK · Classic
RefSeq: WP_021375977.1
GCF_024260145#NMF85_RS10365
NMF85_RS10365 · HK · Classic
RefSeq: WP_021375977.1
GCF_024260215#NMF84_RS01330
NMF84_RS01330 · HK · Classic
RefSeq: WP_021375977.1
GCF_024260265#NMF89_RS04475
NMF89_RS04475 · HK · Classic
RefSeq: WP_021375977.1
GCF_024260515#NMF45_RS03660
NMF45_RS03660 · HK · Classic
RefSeq: WP_021375977.1
GCF_024262205#NMG00_RS10560
NMG00_RS10560 · HK · Classic
RefSeq: WP_021375977.1
GCF_024262325#NMF88_RS03670
NMF88_RS03670 · HK · Classic
RefSeq: WP_021375977.1
GCF_024262365#NMF91_RS00235
NMF91_RS00235 · HK · Classic
RefSeq: WP_021375977.1
GCF_028597315#PSM44_RS09825
PSM44_RS09825 · HK · Classic
RefSeq: WP_021375977.1
GCF_033840445#SIK48_RS02670
SIK48_RS02670 · HK · Classic
RefSeq: WP_021375977.1
GCF_036017135#VXE66_RS04925
VXE66_RS04925 · HK · Classic
RefSeq: WP_021375977.1
GCF_038754145#ABCP49_RS01805
ABCP49_RS01805 · HK · Classic
RefSeq: WP_021375977.1
GCF_038755145#ABCR36_RS04125
ABCR36_RS04125 · HK · Classic
RefSeq: WP_021375977.1
GCF_038755995#ABCQ78_RS07880
ABCQ78_RS07880 · HK · Classic
RefSeq: WP_021375977.1
GCF_043107495#ACGAKC_RS02970
ACGAKC_RS02970 · HK · Classic
RefSeq: WP_021375977.1
GCF_900014225#A4020_RS02420
A4020_RS02420 · HK · Classic
RefSeq: WP_021375977.1
GCF_900096045#DK464_RS02525
DK464_RS02525 · HK · Classic
RefSeq: WP_021375977.1
GCF_900096265#DK487_RS04195
DK487_RS04195 · HK · Classic
RefSeq: WP_021375977.1
GCF_900165935#B2B89_RS05405
B2B89_RS05405 · HK · Classic
RefSeq: WP_021375977.1
GCF_900165975#B2A22_RS04075
B2A22_RS04075 · HK · Classic
RefSeq: WP_021375977.1
GCF_900166005#B2A70_RS02610
B2A70_RS02610 · HK · Classic
RefSeq: WP_021375977.1
GCF_900166015#B2C46_RS02605
B2C46_RS02605 · HK · Classic
RefSeq: WP_021375977.1
GCF_901004505#FJF26_RS02605
FJF26_RS02605 · HK · Classic
RefSeq: WP_021375977.1
GCF_901004865#FJF56_RS01160
FJF56_RS01160 · HK · Classic
RefSeq: WP_021375977.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_024260265
AssemblyASM2426026v1 · Contighaploid
Genome composition3 995 697 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 92 · HK 41 · RR 49CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key