1 HisKA#1
196-255 aa · 60 aa · 14.5% of protein
Raw token
HisKA:196:0.000000000901:255:60:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NMF89_RS02745
Histidine kinase, Classic
Clostridioides difficile · GCF_024260265
ClassHKTypeClassicLength414 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024260265#NMF89_RS02745Stable P2CS identifier used across views.
GenomeGCF_024260265Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length414 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 414 aa (40.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa414 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
301-407 aa · 107 aa · 25.8% of protein
Raw token
HATPase_c:301:8.06e-22:407:107:109- Raw architecture: HisKA:196:0.000000000901:255:60:64#HATPase_c:301:8.06e-22:407:107:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_024260265::NZ_JANCKN010000002.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span186950-188906Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNMF89_02740RefSeq proteinWP_032547333.1
Context group ID
GCF_024260265::NZ_JANCKN010000002.1::G00027Context members
NMF89_RS02740NMF89_RS02745
Partner locus tags
NMF89_RS02740NMF89_RS02745
Partner old locus tags
NMF89_02735NMF89_02740
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_032547333.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNMF89_RS02745Primary locus identifier stored in the genes table.
Old locus tagNMF89_02740Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANCKN010000002.1Sequence record reported by the local genomic context database.
Genomic interval187 662-188 906 nt1 245 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span186 950-188 906 ntGCF_024260265::NZ_JANCKN010000002.1::G00027
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024260265::NZ_JANCKN010000002.1::G00027Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANCKN010000002.1All displayed genes belong to this local TCS context.
Neighborhood span186 950-188 906 nt1 957 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
186 950 nt188 906 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NMF89_RS02740GCF_024260265#NMF89_RS02740
RROmpR
186 950-187 675 nt · Forward (+)
NMF89_RS02745GCF_024260265#NMF89_RS02745
HKClassicCurrent focus
187 662-188 906 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000449185#QCW_RS07395Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2319814
Simplified PFAM architecture for HKOC_2319814
PFAM domain coverage: 169 / 414 aa (40.8%)
1 aa414 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[193-255] | HATPase_c[302-407]
- Domain count: 2
- Matched identifier: HKOC_2319814
- Positioned domains: HisKA 193-255 ; HATPase_c 302-407
Cluster members and taxonomy
Representative gene: GCF_000449185#QCW_RS07395
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_024260265
AssemblyASM2426026v1 · Contighaploid
Genome composition3 995 697 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 92 · HK 41 · RR 49CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key