1 HisKA_3#1
188-253 aa · 66 aa · 17.1% of protein
Raw token
HisKA_3:188:4.07e-20:253:67:68P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NMF81_RS01845
Histidine kinase, Classic
Clostridioides difficile · GCF_024260245
ClassHKTypeClassicLength387 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024260245#NMF81_RS01845Stable P2CS identifier used across views.
GenomeGCF_024260245Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKA_3HATPase_c
Protein length387 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 387 aa (39.0%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
294-378 aa · 85 aa · 22.0% of protein
Raw token
HATPase_c:294:0.00000000019:378:104:109- Raw architecture: HisKA_3:188:4.07e-20:253:67:68#HATPase_c:294:0.00000000019:378:104:109
- Domain description: 1 HisKA_3,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_024260245::NZ_JANCKM010000001.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span382061-383864Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNMF81_01845RefSeq proteinWP_009896183.1
Context group ID
GCF_024260245::NZ_JANCKM010000001.1::G00017Context members
NMF81_RS01845NMF81_RS01850
Partner locus tags
NMF81_RS01845NMF81_RS01850
Partner old locus tags
NMF81_01845NMF81_01850
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009896183.1Primary protein accession used for annex mappings.
UniProt accessionQ18BD5Primary UniProt accession resolved in the annex database.
UniProt IDQ18BD5_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNMF81_RS01845Primary locus identifier stored in the genes table.
Old locus tagNMF81_01845Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANCKM010000001.1Sequence record reported by the local genomic context database.
Genomic interval382 061-383 224 nt1 164 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span382 061-383 864 ntGCF_024260245::NZ_JANCKM010000001.1::G00017
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024260245::NZ_JANCKM010000001.1::G00017Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANCKM010000001.1All displayed genes belong to this local TCS context.
Neighborhood span382 061-383 864 nt1 804 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
382 061 nt383 864 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NMF81_RS01845GCF_024260245#NMF81_RS01845
HKClassicCurrent focus
382 061-383 224 nt · Forward (+)
NMF81_RS01850GCF_024260245#NMF81_RS01850
RRNarL
383 217-383 864 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS07055Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2550063
Simplified PFAM architecture for HKOC_2550063
PFAM domain coverage: 150 / 387 aa (38.8%)
1 aa387 aa
HisKA_3HATPase_c
- Simplified architecture: HisKA_3 + HATPase_c
- Raw architecture: HisKA_3[188-252] | HATPase_c[294-378]
- Domain count: 2
- Matched identifier: HKOC_2550063
- Positioned domains: HisKA_3 188-252 ; HATPase_c 294-378
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS07055
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_024260245
AssemblyASM2426024v1 · Contighaploid
Genome composition4 007 058 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 48 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key