Gene detail

NMF94_RS05985

Histidine kinase, Classic

Clostridioides difficile · GCF_024260185

ClassHKTypeClassicLength663 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_024260185#NMF94_RS05985Stable P2CS identifier used across views.
GenomeGCF_024260185Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0865249Run 6 · 2 sequences · id 100% · cov 80%
External referencesWP_236887127.1 · MIST4 NMF94_RS05985RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length663 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage163 / 663 aa (24.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa663 aa
HisKA: 449-514 aa (66 aa)1HATPase_c: 565-661 aa (97 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
449-514 aa · 66 aa · 10.0% of protein
Raw tokenHisKA:449:0.00000000837:514:66:64
2 HATPase_c#2
565-661 aa · 97 aa · 14.6% of protein
Raw tokenHATPase_c:565:2.1e-27:661:97:109
  • Raw architecture: HisKA:449:0.00000000837:514:66:64#HATPase_c:565:2.1e-27:661:97:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_024260185::NZ_JANCKS010000006.1::G00048
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span40017-45740Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNMF94_05985RefSeq proteinWP_236887127.1
Context group IDGCF_024260185::NZ_JANCKS010000006.1::G00048
Context members
NMF94_RS05970NMF94_RS05975NMF94_RS05980NMF94_RS05985NMF94_RS05990
Partner locus tags
NMF94_RS05970NMF94_RS05975NMF94_RS05980NMF94_RS05985NMF94_RS05990
Partner old locus tags
NMF94_05970NMF94_05975NMF94_05980NMF94_05985NMF94_05990

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_236887127.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNMF94_RS05985Primary locus identifier stored in the genes table.
Old locus tagNMF94_05985Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANCKS010000006.1Sequence record reported by the local genomic context database.
Genomic interval43 000-44 991 nt1 992 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span40 017-45 740 ntGCF_024260185::NZ_JANCKS010000006.1::G00048

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024260185::NZ_JANCKS010000006.1::G00048

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANCKS010000006.1All displayed genes belong to this local TCS context.
Neighborhood span40 017-45 740 nt5 724 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
40 017 nt45 740 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

NMF94_RS05970GCF_024260185#NMF94_RS05970
HKClassic

40 017-41 132 nt · Reverse (-)

Old locus NMF94_05970RefSeq WP_168347315.1
NMF94_RS05975GCF_024260185#NMF94_RS05975
RROmpR

41 168-41 866 nt · Reverse (-)

Old locus NMF94_05975RefSeq WP_102815011.1
NMF94_RS05980GCF_024260185#NMF94_RS05980
RROmpR

42 247-42 927 nt · Reverse (-)

Old locus NMF94_05980RefSeq WP_102814983.1
NMF94_RS05985GCF_024260185#NMF94_RS05985
HKClassicCurrent focus

43 000-44 991 nt · Reverse (-)

Old locus NMF94_05985RefSeq WP_236887127.1
NMF94_RS05990GCF_024260185#NMF94_RS05990
RROmpR

45 063-45 740 nt · Reverse (-)

Old locus NMF94_05990RefSeq WP_003417201.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0865249Run 6 · HK · 2 sequences
Representative sequenceGCF_012276945#GSQ50_RS17265Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0865249

Simplified PFAM architecture for HKOC_0865249

PFAM domain coverage: 164 / 663 aa (24.7%)

1 aa663 aa
HisKA: 450-514 aaHisKAHATPase_c: 563-661 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[450-514] | HATPase_c[563-661]
  • Domain count: 2
  • Matched identifier: HKOC_0865249
  • Positioned domains: HisKA 450-514 ; HATPase_c 563-661
Cluster members and taxonomy
Visualization

Representative gene: GCF_012276945#GSQ50_RS17265

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_024260185
AssemblyASM2426018v1 · Contighaploid
Genome composition4 088 797 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 48 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key