Gene detail

NMF85_RS05150

Histidine kinase, Classic

Clostridioides difficile · GCF_024260145

ClassHKTypeClassicLength462 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_024260145#NMF85_RS05150Stable P2CS identifier used across views.
GenomeGCF_024260145Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1812015Run 6 · 10 sequences · id 100% · cov 80%
External referencesWP_085059761.1 · MIST4 NMF85_RS05150RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length462 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 462 aa (37.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa462 aa
HisKA: 241-305 aa (65 aa)1HATPase_c: 352-460 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
241-305 aa · 65 aa · 14.1% of protein
Raw tokenHisKA:241:0.00000000000149:305:65:64
2 HATPase_c#2
352-460 aa · 109 aa · 23.6% of protein
Raw tokenHATPase_c:352:5.97e-22:460:109:109
  • Raw architecture: HisKA:241:0.00000000000149:305:65:64#HATPase_c:352:5.97e-22:460:109:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_024260145::NZ_JANCKV010000009.1::G00052
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span20845-22233Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNMF85_05140RefSeq proteinWP_085059761.1
Context group IDGCF_024260145::NZ_JANCKV010000009.1::G00052
Context members
NMF85_RS05150
Partner locus tags
NMF85_RS05150
Partner old locus tags
NMF85_05140
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_085059761.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNMF85_RS05150Primary locus identifier stored in the genes table.
Old locus tagNMF85_05140Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANCKV010000009.1Sequence record reported by the local genomic context database.
Genomic interval20 845-22 233 nt1 389 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span20 845-22 233 ntGCF_024260145::NZ_JANCKV010000009.1::G00052

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024260145::NZ_JANCKV010000009.1::G00052

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANCKV010000009.1All displayed genes belong to this local TCS context.
Neighborhood span20 845-22 233 nt1 389 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
20 845 nt22 233 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

NMF85_RS05150GCF_024260145#NMF85_RS05150
HKClassicCurrent focus

20 845-22 233 nt · Forward (+)

Old locus NMF85_05140RefSeq WP_085059761.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1812015Run 6 · HK · 10 sequences
Representative sequenceGCF_012029905#GSQ35_RS02490Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1812015

Simplified PFAM architecture for HKOC_1812015

PFAM domain coverage: 174 / 462 aa (37.7%)

1 aa462 aa
HisKA: 241-305 aaHisKAHATPase_c: 352-460 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[241-305] | HATPase_c[352-460]
  • Domain count: 2
  • Matched identifier: HKOC_1812015
  • Positioned domains: HisKA 241-305 ; HATPase_c 352-460
Cluster members and taxonomy
Visualization

Representative gene: GCF_012029905#GSQ35_RS02490

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_024260145
AssemblyASM2426014v1 · Contighaploid
Genome composition4 130 739 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 90 · HK 41 · RR 47CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key