1 GAF_3#1
159-282 aa · 124 aa · 23.6% of protein
Raw token
GAF_3:159:0.00000229:282:131:129P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NMG01_RS13810
Histidine kinase, Classic
Clostridioides difficile · GCF_024260055
ClassHKTypeClassicLength526 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024260055#NMG01_RS13810Stable P2CS identifier used across views.
GenomeGCF_024260055Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
GAF_3HisKAHATPase_c
Protein length526 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage305 / 526 aa (58.0%)Merged over positioned domains only.
Domain description1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa526 aa
Domain-by-domain annotation3 items
2 HisKA#2
302-369 aa · 68 aa · 12.9% of protein
Raw token
HisKA:302:0.00000000000246:369:68:643 HATPase_c#3
413-525 aa · 113 aa · 21.5% of protein
Raw token
HATPase_c:413:9.82e-31:525:113:109- Raw architecture: GAF_3:159:0.00000229:282:131:129#HisKA:302:0.00000000000246:369:68:64#HATPase_c:413:9.82e-31:525:113:109
- Domain description: 1 GAF_3,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_024260055::NZ_JANCKZ010000115.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1-2315Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNMG01_13840RefSeq proteinWP_254466719.1
Context group ID
GCF_024260055::NZ_JANCKZ010000115.1::G00005Context members
NMG01_RS13810NMG01_RS13815
Partner locus tags
NMG01_RS13810NMG01_RS13815
Partner old locus tags
NMG01_13840NMG01_13845
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_254466719.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNMG01_RS13810Primary locus identifier stored in the genes table.
Old locus tagNMG01_13840Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANCKZ010000115.1Sequence record reported by the local genomic context database.
Genomic interval1-1 583 nt1 583 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-2 315 ntGCF_024260055::NZ_JANCKZ010000115.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024260055::NZ_JANCKZ010000115.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANCKZ010000115.1All displayed genes belong to this local TCS context.
Neighborhood span1-2 315 nt2 315 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt2 315 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NMG01_RS13810GCF_024260055#NMG01_RS13810
HKClassicCurrent focus
1-1 583 nt · Forward (+)
NMG01_RS13815GCF_024260055#NMG01_RS13815
RROmpR
1 617-2 315 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000450785#QO7_RS09300Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0405729
Simplified PFAM architecture for HKOC_0405729
PFAM domain coverage: 494 / 900 aa (54.9%)
1 aa900 aa
KdpDDUF4118HisKAHATPase_c
- Simplified architecture: KdpD + DUF4118 + HisKA + HATPase_c
- Raw architecture: KdpD[22-230] | DUF4118[409-514] | HisKA[676-743] | HATPase_c[788-898]
- Domain count: 4
- Matched identifier: HKOC_0405729
- Positioned domains: KdpD 22-230 ; DUF4118 409-514 ; HisKA 676-743 ; HATPase_c 788-898
Cluster members and taxonomy
Representative gene: GCF_000450785#QO7_RS09300
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_024260055
AssemblyASM2426005v1 · Contighaploid
Genome composition4 186 004 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 49CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key