1 PAS_8#1
484-521 aa · 38 aa · 4.4% of protein
Raw token
PAS_8:484:0.0000704:521:38:65P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NMF99_RS18460
Histidine kinase, Classic
Clostridioides difficile · GCF_024259965
ClassHKTypeClassicLength864 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_024259965#NMF99_RS18460Stable P2CS identifier used across views.
GenomeGCF_024259965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
PAS_8HisKAHATPase_c
Protein length864 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage222 / 864 aa (25.7%)Merged over positioned domains only.
Domain description1 PAS_8,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa864 aa
Domain-by-domain annotation3 items
2 HisKA#2
607-678 aa · 72 aa · 8.3% of protein
Raw token
HisKA:607:0.00000000176:678:72:643 HATPase_c#3
726-837 aa · 112 aa · 13.0% of protein
Raw token
HATPase_c:726:5.27e-26:837:112:109- Raw architecture: PAS_8:484:0.0000704:521:38:65#HisKA:607:0.00000000176:678:72:64#HATPase_c:726:5.27e-26:837:112:109
- Domain description: 1 PAS_8,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_024259965::NZ_JANCLH010000127.1::G00007
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1200-3795Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNMF99_18450RefSeq proteinWP_254469519.1
Context group ID
GCF_024259965::NZ_JANCLH010000127.1::G00007Context members
NMF99_RS18460
Partner locus tags
NMF99_RS18460
Partner old locus tags
NMF99_18450
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_254469519.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNMF99_RS18460Primary locus identifier stored in the genes table.
Old locus tagNMF99_18450Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANCLH010000127.1Sequence record reported by the local genomic context database.
Genomic interval1 200-3 795 nt2 596 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 200-3 795 ntGCF_024259965::NZ_JANCLH010000127.1::G00007
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024259965::NZ_JANCLH010000127.1::G00007Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANCLH010000127.1All displayed genes belong to this local TCS context.
Neighborhood span1 200-3 795 nt2 596 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 200 nt3 795 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
NMF99_RS18460GCF_024259965#NMF99_RS18460
HKClassicCurrent focus
1 200-3 795 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_002301165#BGU11_RS19140Use this link to inspect the representative gene detail.
PFAM architecturePAS_8 + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0388062
Simplified PFAM architecture for HKOC_0388062
PFAM domain coverage: 221 / 912 aa (24.2%)
1 aa912 aa
PAS_8HisKAHATPase_c
- Simplified architecture: PAS_8 + HisKA + HATPase_c
- Raw architecture: PAS_8[532-572] | HisKA[656-724] | HATPase_c[774-884]
- Domain count: 3
- Matched identifier: HKOC_0388062
- Positioned domains: PAS_8 532-572 ; HisKA 656-724 ; HATPase_c 774-884
Cluster members and taxonomy
Representative gene: GCF_002301165#BGU11_RS19140
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_024259965
AssemblyASM2425996v1 · Contighaploid
Genome composition4 076 492 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 48 · RR 52CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key