Gene detail

NMF99_RS10055

Histidine kinase, Classic

Clostridioides difficile · GCF_024259965

ClassHKTypeClassicLength420 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_024259965#NMF99_RS10055Stable P2CS identifier used across views.
GenomeGCF_024259965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1807349Run 6 · 384 sequences · id 100% · cov 80%
External referencesWP_254469492.1 · MIST4 NMF99_RS10055RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length420 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 420 aa (41.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa420 aa
HisKA: 199-263 aa (65 aa)1HATPase_c: 310-418 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
199-263 aa · 65 aa · 15.5% of protein
Raw tokenHisKA:199:0.00000000000137:263:65:64
2 HATPase_c#2
310-418 aa · 109 aa · 26.0% of protein
Raw tokenHATPase_c:310:1.75e-21:418:109:109
  • Raw architecture: HisKA:199:0.00000000000137:263:65:64#HATPase_c:310:1.75e-21:418:109:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_024259965::NZ_JANCLH010000030.1::G00018
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span43406-44670Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNMF99_10055RefSeq proteinWP_254469492.1
Context group IDGCF_024259965::NZ_JANCLH010000030.1::G00018
Context members
NMF99_RS10055
Partner locus tags
NMF99_RS10055
Partner old locus tags
NMF99_10055
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_254469492.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNMF99_RS10055Primary locus identifier stored in the genes table.
Old locus tagNMF99_10055Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANCLH010000030.1Sequence record reported by the local genomic context database.
Genomic interval43 406-44 670 nt1 265 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span43 406-44 670 ntGCF_024259965::NZ_JANCLH010000030.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024259965::NZ_JANCLH010000030.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANCLH010000030.1All displayed genes belong to this local TCS context.
Neighborhood span43 406-44 670 nt1 265 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
43 406 nt44 670 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

NMF99_RS10055GCF_024259965#NMF99_RS10055
HKClassicCurrent focus

43 406-44 670 nt · Reverse (-)

Old locus NMF99_10055RefSeq WP_254469492.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1807349Run 6 · HK · 384 sequences
Representative sequenceGCF_000003215#QAC_RS0206580Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1807349

Simplified PFAM architecture for HKOC_1807349

PFAM domain coverage: 174 / 462 aa (37.7%)

1 aa462 aa
HisKA: 241-305 aaHisKAHATPase_c: 352-460 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[241-305] | HATPase_c[352-460]
  • Domain count: 2
  • Matched identifier: HKOC_1807349
  • Positioned domains: HisKA 241-305 ; HATPase_c 352-460
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0206580

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_024259965
AssemblyASM2425996v1 · Contighaploid
Genome composition4 076 492 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 48 · RR 52CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key