Gene detail

NMF99_RS05345

Histidine kinase, Classic

Clostridioides difficile · GCF_024259965

ClassHKTypeClassicLength912 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_024259965#NMF99_RS05345Stable P2CS identifier used across views.
GenomeGCF_024259965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0388117Run 6 · 10 sequences · id 100% · cov 80%
External referencesWP_102814285.1 · MIST4 NMF99_RS05345RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_8PAS_9HisKAHATPase_c
Protein length912 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage341 / 912 aa (37.4%)Merged over positioned domains only.
Domain description1 PAS_8,1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa912 aa
PAS_8: 302-358 aa (57 aa)1PAS_9: 529-629 aa (101 aa)2HisKA: 655-726 aa (72 aa)3HATPase_c: 773-883 aa (111 aa)4
Domain-by-domain annotation4 items
1 PAS_8#1
302-358 aa · 57 aa · 6.3% of protein
Raw tokenPAS_8:302:0.0000639:358:57:65
2 PAS_9#2
529-629 aa · 101 aa · 11.1% of protein
Raw tokenPAS_9:529:0.0000777:629:101:102
3 HisKA#3
655-726 aa · 72 aa · 7.9% of protein
Raw tokenHisKA:655:0.00000000000000685:726:72:64
4 HATPase_c#4
773-883 aa · 111 aa · 12.2% of protein
Raw tokenHATPase_c:773:3.48e-31:883:111:109
  • Raw architecture: PAS_8:302:0.0000639:358:57:65#PAS_9:529:0.0000777:629:101:102#HisKA:655:0.00000000000000685:726:72:64#HATPase_c:773:3.48e-31:883:111:109
  • Domain description: 1 PAS_8,1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_024259965::NZ_JANCLH010000012.1::G00008
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span26158-28896Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNMF99_05345RefSeq proteinWP_102814285.1
Context group IDGCF_024259965::NZ_JANCLH010000012.1::G00008
Context members
NMF99_RS05345
Partner locus tags
NMF99_RS05345
Partner old locus tags
NMF99_05345
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_102814285.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNMF99_RS05345Primary locus identifier stored in the genes table.
Old locus tagNMF99_05345Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANCLH010000012.1Sequence record reported by the local genomic context database.
Genomic interval26 158-28 896 nt2 739 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span26 158-28 896 ntGCF_024259965::NZ_JANCLH010000012.1::G00008

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024259965::NZ_JANCLH010000012.1::G00008

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANCLH010000012.1All displayed genes belong to this local TCS context.
Neighborhood span26 158-28 896 nt2 739 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
26 158 nt28 896 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

NMF99_RS05345GCF_024259965#NMF99_RS05345
HKClassicCurrent focus

26 158-28 896 nt · Forward (+)

Old locus NMF99_05345RefSeq WP_102814285.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0388117Run 6 · HK · 10 sequences
Representative sequenceGCF_002891605#AMR89_RS00835Use this link to inspect the representative gene detail.
PFAM architecturePAS_8 + PAS_9 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0388117

Simplified PFAM architecture for HKOC_0388117

PFAM domain coverage: 340 / 912 aa (37.3%)

1 aa912 aa
PAS_8: 303-355 aaPAS_8PAS_9: 529-632 aaPAS_9HisKA: 655-726 aaHisKAHATPase_c: 773-883 aaHATPase_c
PAS_8PAS_9HisKAHATPase_c
  • Simplified architecture: PAS_8 + PAS_9 + HisKA + HATPase_c
  • Raw architecture: PAS_8[303-355] | PAS_9[529-632] | HisKA[655-726] | HATPase_c[773-883]
  • Domain count: 4
  • Matched identifier: HKOC_0388117
  • Positioned domains: PAS_8 303-355 ; PAS_9 529-632 ; HisKA 655-726 ; HATPase_c 773-883
Cluster members and taxonomy
Visualization

Representative gene: GCF_002891605#AMR89_RS00835

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_024259965
AssemblyASM2425996v1 · Contighaploid
Genome composition4 076 492 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 48 · RR 52CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key