1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw token
HisKA:148:0.0000000000000882:211:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NMF99_RS02350
Histidine kinase, Classic
Clostridioides difficile · GCF_024259965
ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_024259965#NMF99_RS02350Stable P2CS identifier used across views.
GenomeGCF_024259965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa371 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw token
HATPase_c:260:4.62e-25:368:110:109- Raw architecture: HisKA:148:0.0000000000000882:211:64:64#HATPase_c:260:4.62e-25:368:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labeltriadGCF_024259965::NZ_JANCLH010000005.1::G00035
Group size33 locus tags listed below.
HK / RR1 / 2Counts resolved for the local TCS neighborhood.
Context span14065-16977Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNMF99_02350RefSeq proteinWP_107578576.1
Context group ID
GCF_024259965::NZ_JANCLH010000005.1::G00035Context members
NMF99_RS02350NMF99_RS02355NMF99_RS02360
Partner locus tags
NMF99_RS02350NMF99_RS02355NMF99_RS02360
Partner old locus tags
NMF99_02350NMF99_02355NMF99_02360
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_107578576.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNMF99_RS02350Primary locus identifier stored in the genes table.
Old locus tagNMF99_02350Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANCLH010000005.1Sequence record reported by the local genomic context database.
Genomic interval14 065-15 180 nt1 116 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span14 065-16 977 ntGCF_024259965::NZ_JANCLH010000005.1::G00035
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024259965::NZ_JANCLH010000005.1::G00035Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANCLH010000005.1All displayed genes belong to this local TCS context.
Neighborhood span14 065-16 977 nt2 913 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
14 065 nt16 977 nt
Neighborhood gene cards
3 genes in the current local neighborhood.
NMF99_RS02350GCF_024259965#NMF99_RS02350
HKClassicCurrent focus
14 065-15 180 nt · Reverse (-)
NMF99_RS02355GCF_024259965#NMF99_RS02355
RROmpR
15 216-15 914 nt · Reverse (-)
NMF99_RS02360GCF_024259965#NMF99_RS02360
RROmpR
16 297-16 977 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_024259965#NMF99_RS02350The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2679320
Simplified PFAM architecture for HKOC_2679320
PFAM domain coverage: 174 / 371 aa (46.9%)
1 aa371 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[149-213] | HATPase_c[261-369]
- Domain count: 2
- Matched identifier: HKOC_2679320
- Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Representative gene: GCF_024259965#NMF99_RS02350
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_024259965
AssemblyASM2425996v1 · Contighaploid
Genome composition4 076 492 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 48 · RR 52CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key