1 HisKA#1
137-201 aa · 65 aa · 17.8% of protein
Raw token
HisKA:137:0.00000000000986:201:65:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NB460_RS10650
Histidine kinase, Classic
Clostridioides difficile · GCF_023656875
ClassHKTypeClassicLength366 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_023656875#NB460_RS10650Stable P2CS identifier used across views.
GenomeGCF_023656875Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length366 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage183 / 366 aa (50.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa366 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
248-365 aa · 118 aa · 32.2% of protein
Raw token
HATPase_c:248:5.73e-19:365:119:109- Raw architecture: HisKA:137:0.00000000000986:201:65:64#HATPase_c:248:5.73e-19:365:119:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_023656875::NZ_JAMOJW010000001.1::G00036
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2224208-2226137Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNB460_10645RefSeq proteinWP_250781634.1
Context group ID
GCF_023656875::NZ_JAMOJW010000001.1::G00036Context members
NB460_RS10650NB460_RS10655
Partner locus tags
NB460_RS10650NB460_RS10655
Partner old locus tags
NB460_10645NB460_10650
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_250781634.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNB460_RS10650Primary locus identifier stored in the genes table.
Old locus tagNB460_10645Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAMOJW010000001.1Sequence record reported by the local genomic context database.
Genomic interval2 224 208-2 225 308 nt1 101 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 224 208-2 226 137 ntGCF_023656875::NZ_JAMOJW010000001.1::G00036
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_023656875::NZ_JAMOJW010000001.1::G00036Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAMOJW010000001.1All displayed genes belong to this local TCS context.
Neighborhood span2 224 208-2 226 137 nt1 930 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 224 208 nt2 226 137 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NB460_RS10650GCF_023656875#NB460_RS10650
HKClassicCurrent focus
2 224 208-2 225 308 nt · Reverse (-)
NB460_RS10655GCF_023656875#NB460_RS10655
RROmpR
2 225 469-2 226 137 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_023656875#NB460_RS10650The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2715464
Simplified PFAM architecture for HKOC_2715464
PFAM domain coverage: 179 / 366 aa (48.9%)
1 aa366 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[138-201] | HATPase_c[249-363]
- Domain count: 2
- Matched identifier: HKOC_2715464
- Positioned domains: HisKA 138-201 ; HATPase_c 249-363
Cluster members and taxonomy
Representative gene: GCF_023656875#NB460_RS10650
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_023656875
AssemblyASM2365687v1 · Scaffoldhaploid
Genome composition4 174 231 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 46 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key