Gene detail

NB460_RS02760

Histidine kinase, Classic

Clostridioides difficile · GCF_023656875

ClassHKTypeClassicLength464 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_023656875#NB460_RS02760Stable P2CS identifier used across views.
GenomeGCF_023656875Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1786178Run 6 · 6 sequences · id 100% · cov 80%
External referencesWP_102815407.1 · MIST4 NB460_RS02760RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length464 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage213 / 464 aa (45.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa464 aa
HAMP: 170-237 aa (68 aa)1HisKA: 249-308 aa (60 aa)2HATPase_c: 355-439 aa (85 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
170-237 aa · 68 aa · 14.7% of protein
Raw tokenHAMP:170:0.00000000000035:237:68:69
2 HisKA#2
249-308 aa · 60 aa · 12.9% of protein
Raw tokenHisKA:249:0.000000000624:308:61:64
3 HATPase_c#3
355-439 aa · 85 aa · 18.3% of protein
Raw tokenHATPase_c:355:0.0000000000000173:439:88:109
  • Raw architecture: HAMP:170:0.00000000000035:237:68:69#HisKA:249:0.000000000624:308:61:64#HATPase_c:355:0.0000000000000173:439:88:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_023656875::NZ_JAMOJW010000001.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span526159-528193Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNB460_02755RefSeq proteinWP_102815407.1
Context group IDGCF_023656875::NZ_JAMOJW010000001.1::G00006
Context members
NB460_RS02755NB460_RS02760
Partner locus tags
NB460_RS02755NB460_RS02760
Partner old locus tags
NB460_02750NB460_02755
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_102815407.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNB460_RS02760Primary locus identifier stored in the genes table.
Old locus tagNB460_02755Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAMOJW010000001.1Sequence record reported by the local genomic context database.
Genomic interval526 799-528 193 nt1 395 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span526 159-528 193 ntGCF_023656875::NZ_JAMOJW010000001.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_023656875::NZ_JAMOJW010000001.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAMOJW010000001.1All displayed genes belong to this local TCS context.
Neighborhood span526 159-528 193 nt2 035 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
526 159 nt528 193 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NB460_RS02755GCF_023656875#NB460_RS02755
RROmpR

526 159-526 806 nt · Forward (+)

Old locus NB460_02750RefSeq WP_021407727.1
NB460_RS02760GCF_023656875#NB460_RS02760
HKClassicCurrent focus

526 799-528 193 nt · Forward (+)

Old locus NB460_02755RefSeq WP_102815407.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1786178Run 6 · HK · 6 sequences
Representative sequenceGCF_002891605#AMR89_RS16340Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1786178

Simplified PFAM architecture for HKOC_1786178

PFAM domain coverage: 195 / 464 aa (42.0%)

1 aa464 aa
HAMP: 187-236 aaHAMPHisKA: 250-308 aaHisKAHATPase_c: 355-440 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[187-236] | HisKA[250-308] | HATPase_c[355-440]
  • Domain count: 3
  • Matched identifier: HKOC_1786178
  • Positioned domains: HAMP 187-236 ; HisKA 250-308 ; HATPase_c 355-440
Cluster members and taxonomy
Visualization

Representative gene: GCF_002891605#AMR89_RS16340

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_023656875
AssemblyASM2365687v1 · Scaffoldhaploid
Genome composition4 174 231 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 46 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key