1 HAMP#1
127-204 aa · 78 aa · 17.7% of protein
Raw token
HAMP:127:0.00000000636:204:78:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NBN67_RS02355
Histidine kinase, Classic
Clostridioides difficile · GCF_023656865
ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_023656865#NBN67_RS02355Stable P2CS identifier used across views.
GenomeGCF_023656865Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 440 aa (57.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
Domain-by-domain annotation3 items
2 HisKA#2
216-281 aa · 66 aa · 15.0% of protein
Raw token
HisKA:216:0.00000000144:281:66:643 HATPase_c#3
331-437 aa · 107 aa · 24.3% of protein
Raw token
HATPase_c:331:1.01e-26:437:107:109- Raw architecture: HAMP:127:0.00000000636:204:78:69#HisKA:216:0.00000000144:281:66:64#HATPase_c:331:1.01e-26:437:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_023656865::NZ_JAMOJX010000001.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span458677-460812Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNBN67_02350RefSeq proteinWP_330556234.1
Context group ID
GCF_023656865::NZ_JAMOJX010000001.1::G00005Context members
NBN67_RS02350NBN67_RS02355
Partner locus tags
NBN67_RS02350NBN67_RS02355
Partner old locus tags
NBN67_02345NBN67_02350
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_330556234.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNBN67_RS02355Primary locus identifier stored in the genes table.
Old locus tagNBN67_02350Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAMOJX010000001.1Sequence record reported by the local genomic context database.
Genomic interval459 490-460 812 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span458 677-460 812 ntGCF_023656865::NZ_JAMOJX010000001.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_023656865::NZ_JAMOJX010000001.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAMOJX010000001.1All displayed genes belong to this local TCS context.
Neighborhood span458 677-460 812 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
458 677 nt460 812 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NBN67_RS02350GCF_023656865#NBN67_RS02350
RROmpR
458 677-459 369 nt · Forward (+)
NBN67_RS02355GCF_023656865#NBN67_RS02355
HKClassicCurrent focus
459 490-460 812 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004315425#E0P58_RS14930Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2074573
Simplified PFAM architecture for HKOC_2074573
PFAM domain coverage: 223 / 440 aa (50.7%)
1 aa440 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[154-204] | HisKA[217-281] | HATPase_c[331-437]
- Domain count: 3
- Matched identifier: HKOC_2074573
- Positioned domains: HAMP 154-204 ; HisKA 217-281 ; HATPase_c 331-437
Cluster members and taxonomy
Representative gene: GCF_004315425#E0P58_RS14930
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_023656865
AssemblyASM2365686v1 · Scaffoldhaploid
Genome composition4 457 763 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 46 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key