1 HisKA#1
241-305 aa · 65 aa · 14.1% of protein
Raw token
HisKA:241:0.00000000000123:305:65:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWC40_RS06870
Histidine kinase, Classic
Clostridioides difficile · GCF_022695655
ClassHKTypeClassicLength462 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_022695655#LWC40_RS06870Stable P2CS identifier used across views.
GenomeGCF_022695655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length462 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 462 aa (37.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
352-460 aa · 109 aa · 23.6% of protein
Raw token
HATPase_c:352:3.94e-21:460:109:109- Raw architecture: HisKA:241:0.00000000000123:305:65:64#HATPase_c:352:3.94e-21:460:109:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_022695655::NZ_CP090060.1::G00022
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1457552-1458940Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWC40_06870RefSeq proteinWP_011861185.1
Context group ID
GCF_022695655::NZ_CP090060.1::G00022Context members
LWC40_RS06870
Partner locus tags
LWC40_RS06870
Partner old locus tags
LWC40_06870
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_011861185.1Primary protein accession used for annex mappings.
UniProt accessionQ18BL5Primary UniProt accession resolved in the annex database.
UniProt IDQ18BL5_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWC40_RS06870Primary locus identifier stored in the genes table.
Old locus tagLWC40_06870Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP090060.1Sequence record reported by the local genomic context database.
Genomic interval1 457 552-1 458 940 nt1 389 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 457 552-1 458 940 ntGCF_022695655::NZ_CP090060.1::G00022
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_022695655::NZ_CP090060.1::G00022Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP090060.1All displayed genes belong to this local TCS context.
Neighborhood span1 457 552-1 458 940 nt1 389 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 457 552 nt1 458 940 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
LWC40_RS06870GCF_022695655#LWC40_RS06870
HKClassicCurrent focus
1 457 552-1 458 940 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS07470Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1807357
Simplified PFAM architecture for HKOC_1807357
PFAM domain coverage: 174 / 462 aa (37.7%)
1 aa462 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[241-305] | HATPase_c[352-460]
- Domain count: 2
- Matched identifier: HKOC_1807357
- Positioned domains: HisKA 241-305 ; HATPase_c 352-460
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS07470
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_022695655
AssemblyASM2269565v1 · Complete Genomehaploid
Genome composition4 234 172 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key