1 HAMP#1
84-152 aa · 69 aa · 17.9% of protein
Raw token
HAMP:84:0.000000704:152:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWC40_RS02855
Histidine kinase, Classic
Clostridioides difficile · GCF_022695655
ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_022695655#LWC40_RS02855Stable P2CS identifier used across views.
GenomeGCF_022695655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 386 aa (59.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa386 aa
Domain-by-domain annotation3 items
2 HisKA#2
164-217 aa · 54 aa · 14.0% of protein
Raw token
HisKA:164:0.0000000505:217:54:643 HATPase_c#3
278-382 aa · 105 aa · 27.2% of protein
Raw token
HATPase_c:278:3.45e-21:382:106:109- Raw architecture: HAMP:84:0.000000704:152:70:69#HisKA:164:0.0000000505:217:54:64#HATPase_c:278:3.45e-21:382:106:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_022695655::NZ_CP090060.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span541132-542954Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWC40_02855RefSeq proteinWP_021361763.1
Context group ID
GCF_022695655::NZ_CP090060.1::G00008Context members
LWC40_RS02855LWC40_RS02860
Partner locus tags
LWC40_RS02855LWC40_RS02860
Partner old locus tags
LWC40_02855LWC40_02860
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021361763.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWC40_RS02855Primary locus identifier stored in the genes table.
Old locus tagLWC40_02855Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP090060.1Sequence record reported by the local genomic context database.
Genomic interval541 132-542 292 nt1 161 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span541 132-542 954 ntGCF_022695655::NZ_CP090060.1::G00008
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_022695655::NZ_CP090060.1::G00008Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP090060.1All displayed genes belong to this local TCS context.
Neighborhood span541 132-542 954 nt1 823 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
541 132 nt542 954 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
LWC40_RS02855GCF_022695655#LWC40_RS02855
HKClassicCurrent focus
541 132-542 292 nt · Reverse (-)
LWC40_RS02860GCF_022695655#LWC40_RS02860
RROmpR
542 280-542 954 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS02975Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2557604
Simplified PFAM architecture for HKOC_2557604
PFAM domain coverage: 220 / 386 aa (57.0%)
1 aa386 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[106-151] | HisKA[164-231] | HATPase_c[278-383]
- Domain count: 3
- Matched identifier: HKOC_2557604
- Positioned domains: HAMP 106-151 ; HisKA 164-231 ; HATPase_c 278-383
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS02975
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_022695655
AssemblyASM2269565v1 · Complete Genomehaploid
Genome composition4 234 172 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key