1 HisKA#1
46-109 aa · 64 aa · 24.2% of protein
Raw token
HisKA:46:0.00000000000329:109:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWC40_RS02405
Histidine kinase, Classic
Clostridioides difficile · GCF_022695655
ClassHKTypeClassicLength265 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_022695655#LWC40_RS02405Stable P2CS identifier used across views.
GenomeGCF_022695655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length265 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage169 / 265 aa (63.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa265 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
156-260 aa · 105 aa · 39.6% of protein
Raw token
HATPase_c:156:4.74e-28:260:105:109- Raw architecture: HisKA:46:0.00000000000329:109:64:64#HATPase_c:156:4.74e-28:260:105:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_022695655::NZ_CP090060.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span443803-445406Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWC40_02405RefSeq proteinWP_231299186.1
Context group ID
GCF_022695655::NZ_CP090060.1::G00005Context members
LWC40_RS02405LWC40_RS02410
Partner locus tags
LWC40_RS02405LWC40_RS02410
Partner old locus tags
LWC40_02405LWC40_02410
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_231299186.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWC40_RS02405Primary locus identifier stored in the genes table.
Old locus tagLWC40_02405Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP090060.1Sequence record reported by the local genomic context database.
Genomic interval443 803-444 600 nt798 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span443 803-445 406 ntGCF_022695655::NZ_CP090060.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_022695655::NZ_CP090060.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP090060.1All displayed genes belong to this local TCS context.
Neighborhood span443 803-445 406 nt1 604 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
443 803 nt445 406 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
LWC40_RS02405GCF_022695655#LWC40_RS02405
HKClassicCurrent focus
443 803-444 600 nt · Reverse (-)
LWC40_RS02410GCF_022695655#LWC40_RS02410
RROmpR
444 714-445 406 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS02380Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2910172
Simplified PFAM architecture for HKOC_2910172
PFAM domain coverage: 169 / 265 aa (63.8%)
1 aa265 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[46-109] | HATPase_c[156-260]
- Domain count: 2
- Matched identifier: HKOC_2910172
- Positioned domains: HisKA 46-109 ; HATPase_c 156-260
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS02380
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_022695655
AssemblyASM2269565v1 · Complete Genomehaploid
Genome composition4 234 172 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key