1 Response_reg#1
4-112 aa · 109 aa · 55.6% of protein
Raw token
Response_reg:4:6.12e-32:112:112:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HZT08_RS00180
Response regulator, unclassified
Shigella flexneri · GCF_022494435
ClassRRTypeunclassifiedLength196 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_022494435#HZT08_RS00180Stable P2CS identifier used across views.
GenomeGCF_022494435Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Domain signature
Compact overview inferred from the domain field
Response_regGerE
Protein length196 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage164 / 196 aa (83.7%)Merged over positioned domains only.
Domain description1 Response_reg,1 GerESummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa196 aa
Domain-by-domain annotation2 items
2 GerE#2
136-190 aa · 55 aa · 28.1% of protein
Raw token
GerE:136:4.01e-25:190:55:57- Raw architecture: Response_reg:4:6.12e-32:112:112:111#GerE:136:4.01e-25:190:55:57
- Domain description: 1 Response_reg,1 GerE
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_022494435::NZ_CP058790.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span33145-35237Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHZT08_00175RefSeq proteinWP_000633668.1
Context group ID
GCF_022494435::NZ_CP058790.1::G00001Context members
HZT08_RS00180HZT08_RS00185
Partner locus tags
HZT08_RS00180HZT08_RS00185
Partner old locus tags
HZT08_00175HZT08_00180
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000633668.1Primary protein accession used for annex mappings.
UniProt accessionD3H2G8Primary UniProt accession resolved in the annex database.
UniProt IDD3H2G8_ECO44Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHZT08_RS00180Primary locus identifier stored in the genes table.
Old locus tagHZT08_00175Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP058790.1Sequence record reported by the local genomic context database.
Genomic interval33 145-33 735 nt591 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span33 145-35 237 ntGCF_022494435::NZ_CP058790.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_022494435::NZ_CP058790.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP058790.1All displayed genes belong to this local TCS context.
Neighborhood span33 145-35 237 nt2 093 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
33 145 nt35 237 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HZT08_RS00180GCF_022494435#HZT08_RS00180
RRunclassifiedCurrent focus
33 145-33 735 nt · Forward (+)
HZT08_RS00185GCF_022494435#HZT08_RS00185
HKClassic
33 735-35 237 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureResponse_reg + GerE2 domains in the representative PFAM annotation.
PFAM architecture for RROC_2154829
Simplified PFAM architecture for RROC_2154829
PFAM domain coverage: 165 / 196 aa (84.2%)
1 aa196 aa
Response_regGerE
- Simplified architecture: Response_reg + GerE
- Raw architecture: Response_reg[4-112] | GerE[136-191]
- Domain count: 2
- Matched identifier: RROC_2154829
- Positioned domains: Response_reg 4-112 ; Response_reg 4-112 ; GerE 136-191 ; GerE 136-191
Cluster members and taxonomy
Representative gene: GCF_000005845#b3669
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 623 · GCF_022494435
AssemblyASM2249443v1 · Complete Genomehaploid
Genome composition4 998 483 bp · 50,5% GCShigella flexneri
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella
Related genes
Preview from the same derived genome key