1 His_kinase#1
205-283 aa · 79 aa · 19.8% of protein
Raw token
His_kinase:205:2.35e-31:283:80:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWE98_RS11300
Histidine kinase, Classic
Clostridioides difficile · GCF_021284575
ClassHKTypeClassicLength400 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284575#LWE98_RS11300Stable P2CS identifier used across views.
GenomeGCF_021284575Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length400 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 400 aa (45.0%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa400 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
300-400 aa · 101 aa · 25.3% of protein
Raw token
HATPase_c:300:0.00000000142:400:108:109- Raw architecture: His_kinase:205:2.35e-31:283:80:80#HATPase_c:300:0.00000000142:400:108:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_021284575::NZ_JAJSND010000201.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4868-6845Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE98_11325RefSeq proteinWP_016729404.1
Context group ID
GCF_021284575::NZ_JAJSND010000201.1::G00012Context members
LWE98_RS11295LWE98_RS11300
Partner locus tags
LWE98_RS11295LWE98_RS11300
Partner old locus tags
LWE98_11320LWE98_11325
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_016729404.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWE98_RS11300Primary locus identifier stored in the genes table.
Old locus tagLWE98_11325Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSND010000201.1Sequence record reported by the local genomic context database.
Genomic interval5 643-6 845 nt1 203 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 868-6 845 ntGCF_021284575::NZ_JAJSND010000201.1::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_021284575::NZ_JAJSND010000201.1::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSND010000201.1All displayed genes belong to this local TCS context.
Neighborhood span4 868-6 845 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 868 nt6 845 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
LWE98_RS11295GCF_021284575#LWE98_RS11295
RRLytTR
4 868-5 638 nt · Reverse (-)
LWE98_RS11300GCF_021284575#LWE98_RS11300
HKClassicCurrent focus
5 643-6 845 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000242355#MUI_RS0115660Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2440652
Simplified PFAM architecture for HKOC_2440652
PFAM domain coverage: 342 / 400 aa (85.5%)
1 aa400 aa
5TM-5TMR_LYTHis_kinaseHATPase_c
- Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
- Raw architecture: 5TM-5TMR_LYT[27-190] | His_kinase[205-281] | HATPase_c[299-399]
- Domain count: 3
- Matched identifier: HKOC_2440652
- Positioned domains: 5TM-5TMR_LYT 27-190 ; His_kinase 205-281 ; HATPase_c 299-399
Cluster members and taxonomy
Representative gene: GCF_000242355#MUI_RS0115660
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284575
AssemblyASM2128457v1 · Contighaploid
Genome composition4 114 732 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 49 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key