Gene detail

LWF13_RS01875

Histidine kinase, Classic

Clostridioides difficile · GCF_021284545

ClassHKTypeClassicLength360 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284545#LWF13_RS01875Stable P2CS identifier used across views.
GenomeGCF_021284545Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2746944Run 6 · 785 sequences · id 100% · cov 80%
External referencesWP_012816161.1 · A0A0H3N707 · MIST4 LWF13_RS01875RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length360 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 360 aa (44.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa360 aa
HisKA: 135-198 aa (64 aa)1HATPase_c: 248-344 aa (97 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
135-198 aa · 64 aa · 17.8% of protein
Raw tokenHisKA:135:0.000000000000365:198:64:64
2 HATPase_c#2
248-344 aa · 97 aa · 26.9% of protein
Raw tokenHATPase_c:248:2.05e-21:344:97:109
  • Raw architecture: HisKA:135:0.000000000000365:198:64:64#HATPase_c:248:2.05e-21:344:97:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021284545::NZ_JAJSMW010000016.1::G00053
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span10406-12239Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWF13_01880RefSeq proteinWP_012816161.1
Context group IDGCF_021284545::NZ_JAJSMW010000016.1::G00053
Context members
LWF13_RS01875LWF13_RS01880
Partner locus tags
LWF13_RS01875LWF13_RS01880
Partner old locus tags
LWF13_01880LWF13_01885
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_012816161.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N707Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N707_CLODCDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWF13_RS01875Primary locus identifier stored in the genes table.
Old locus tagLWF13_01880Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSMW010000016.1Sequence record reported by the local genomic context database.
Genomic interval10 406-11 488 nt1 083 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span10 406-12 239 ntGCF_021284545::NZ_JAJSMW010000016.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284545::NZ_JAJSMW010000016.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSMW010000016.1All displayed genes belong to this local TCS context.
Neighborhood span10 406-12 239 nt1 834 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
10 406 nt12 239 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWF13_RS01875GCF_021284545#LWF13_RS01875
HKClassicCurrent focus

10 406-11 488 nt · Reverse (-)

Old locus LWF13_01880RefSeq WP_012816161.1
LWF13_RS01880GCF_021284545#LWF13_RS01880
RROmpR

11 538-12 239 nt · Reverse (-)

Old locus LWF13_01885RefSeq WP_003436401.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2746944Run 6 · HK · 785 sequences
Representative sequenceGCF_000003215#QAC_RS0208405Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2746944

Simplified PFAM architecture for HKOC_2746944

PFAM domain coverage: 161 / 360 aa (44.7%)

1 aa360 aa
HisKA: 136-198 aaHisKAHATPase_c: 248-345 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[136-198] | HATPase_c[248-345]
  • Domain count: 2
  • Matched identifier: HKOC_2746944
  • Positioned domains: HisKA 136-198 ; HATPase_c 248-345
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0208405

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284545
AssemblyASM2128454v1 · Contighaploid
Genome composition4 216 063 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 46 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key