Gene detail

LWF07_RS12545

Histidine kinase, CheA

Clostridioides difficile · GCF_021284495

ClassHKTypeCheALength444 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_021284495#LWF07_RS12545Stable P2CS identifier used across views.
GenomeGCF_021284495Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0768912Run 6 · 527 sequences · id 100% · cov 80%
External referencesWP_232887792.1 · MIST4 LWF07_RS12545RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

H-kinase_dimHATPase_cCheW
Protein length444 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage337 / 444 aa (75.9%)Merged over positioned domains only.
Domain description1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa444 aa
H-kinase_dim: 56-117 aa (62 aa)1HATPase_c: 164-303 aa (140 aa)2CheW: 308-442 aa (135 aa)3
Domain-by-domain annotation3 items
1 H-kinase_dim#1
56-117 aa · 62 aa · 14.0% of protein
Raw tokenH-kinase_dim:56:0.00000000000000404:117:67:67
2 HATPase_c#2
164-303 aa · 140 aa · 31.5% of protein
Raw tokenHATPase_c:164:6.07e-17:303:140:109
3 CheW#3
308-442 aa · 135 aa · 30.4% of protein
Raw tokenCheW:308:4.27e-22:442:136:138
  • Raw architecture: H-kinase_dim:56:0.00000000000000404:117:67:67#HATPase_c:164:6.07e-17:303:140:109#CheW:308:4.27e-22:442:136:138
  • Domain description: 1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_021284495::NZ_JAJSNU010000229.1::G00034
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span4747-6082Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWF07_12580RefSeq proteinWP_232887792.1
Context group IDGCF_021284495::NZ_JAJSNU010000229.1::G00034
Context members
LWF07_RS12545
Partner locus tags
LWF07_RS12545
Partner old locus tags
LWF07_12580
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_232887792.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWF07_RS12545Primary locus identifier stored in the genes table.
Old locus tagLWF07_12580Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNU010000229.1Sequence record reported by the local genomic context database.
Genomic interval4 747-6 082 nt1 336 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 747-6 082 ntGCF_021284495::NZ_JAJSNU010000229.1::G00034

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284495::NZ_JAJSNU010000229.1::G00034

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNU010000229.1All displayed genes belong to this local TCS context.
Neighborhood span4 747-6 082 nt1 336 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 747 nt6 082 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

LWF07_RS12545GCF_021284495#LWF07_RS12545
HKCheACurrent focus

4 747-6 082 nt · Reverse (-)

Old locus LWF07_12580RefSeq WP_232887792.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0768912Run 6 · HK · 527 sequences
Representative sequenceGCF_000009205#CD630_RS03265Use this link to inspect the representative gene detail.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0768912

Simplified PFAM architecture for HKOC_0768912

PFAM domain coverage: 513 / 700 aa (73.3%)

1 aa700 aa
Hpt: 3-104 aaHptP2: 164-240 aaP2H-kinase_dim: 312-373 aaH-kinase_dimHATPase_c: 422-559 aaHATPase_cCheW: 565-698 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[3-104] | P2[164-240] | H-kinase_dim[312-373] | HATPase_c[422-559] | CheW[565-698]
  • Domain count: 5
  • Matched identifier: HKOC_0768912
  • Positioned domains: Hpt 3-104 ; P2 164-240 ; H-kinase_dim 312-373 ; HATPase_c 422-559 ; CheW 565-698
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS03265

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284495
AssemblyASM2128449v1 · Contighaploid
Genome composition4 098 148 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 108 · HK 51 · RR 56CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key