Gene detail

LWE75_RS06305

Histidine kinase, Classic

Clostridioides difficile · GCF_021284485

ClassHKTypeClassicLength328 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_021284485#LWE75_RS06305Stable P2CS identifier used across views.
GenomeGCF_021284485Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1351418Run 6 · 59 sequences · id 100% · cov 80%
External referencesWP_141247717.1 · MIST4 LWE75_RS06305RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length328 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 328 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa328 aa
HisKA: 107-173 aa (67 aa)1HATPase_c: 226-311 aa (86 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
107-173 aa · 67 aa · 20.4% of protein
Raw tokenHisKA:107:0.0000000000000173:173:67:64
2 HATPase_c#2
226-311 aa · 86 aa · 26.2% of protein
Raw tokenHATPase_c:226:0.0000000662:311:90:109
  • Raw architecture: HisKA:107:0.0000000000000173:173:67:64#HATPase_c:226:0.0000000662:311:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_021284485::NZ_JAJSNR010000091.1::G00016
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span8897-9884Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE75_06300RefSeq proteinWP_141247717.1
Context group IDGCF_021284485::NZ_JAJSNR010000091.1::G00016
Context members
LWE75_RS06305
Partner locus tags
LWE75_RS06305
Partner old locus tags
LWE75_06300
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_141247717.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE75_RS06305Primary locus identifier stored in the genes table.
Old locus tagLWE75_06300Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNR010000091.1Sequence record reported by the local genomic context database.
Genomic interval8 897-9 884 nt988 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span8 897-9 884 ntGCF_021284485::NZ_JAJSNR010000091.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284485::NZ_JAJSNR010000091.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNR010000091.1All displayed genes belong to this local TCS context.
Neighborhood span8 897-9 884 nt988 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 897 nt9 884 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

LWE75_RS06305GCF_021284485#LWE75_RS06305
HKClassicCurrent focus

8 897-9 884 nt · Reverse (-)

Old locus LWE75_06300RefSeq WP_141247717.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1351418Run 6 · HK · 59 sequences
Representative sequenceGCF_900243095#DBQ06_RS06465Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1351418

Simplified PFAM architecture for HKOC_1351418

PFAM domain coverage: 191 / 532 aa (35.9%)

1 aa532 aa
HAMP: 257-297 aaHAMPHisKA: 312-377 aaHisKAHATPase_c: 429-512 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[257-297] | HisKA[312-377] | HATPase_c[429-512]
  • Domain count: 3
  • Matched identifier: HKOC_1351418
  • Positioned domains: HAMP 257-297 ; HisKA 312-377 ; HATPase_c 429-512
Cluster members and taxonomy
Visualization

Representative gene: GCF_900243095#DBQ06_RS06465

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284485
AssemblyASM2128448v1 · Contighaploid
Genome composition4 077 225 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key