Gene detail

LWE84_RS09535

Histidine kinase, Classic

Clostridioides difficile · GCF_021284455

ClassHKTypeClassicLength319 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284455#LWE84_RS09535Stable P2CS identifier used across views.
GenomeGCF_021284455Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2550189Run 6 · 65 sequences · id 100% · cov 80%
External referencesWP_232915349.1 · MIST4 LWE84_RS09535RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length319 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 319 aa (47.3%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa319 aa
HisKA_3: 120-185 aa (66 aa)1HATPase_c: 226-310 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
120-185 aa · 66 aa · 20.7% of protein
Raw tokenHisKA_3:120:1.6e-20:185:67:68
2 HATPase_c#2
226-310 aa · 85 aa · 26.6% of protein
Raw tokenHATPase_c:226:0.000000000119:310:104:109
  • Raw architecture: HisKA_3:120:1.6e-20:185:67:68#HATPase_c:226:0.000000000119:310:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021284455::NZ_JAJSNS010000148.1::G00042
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6529-8128Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE84_09535RefSeq proteinWP_232915349.1
Context group IDGCF_021284455::NZ_JAJSNS010000148.1::G00042
Context members
LWE84_RS09530LWE84_RS09535
Partner locus tags
LWE84_RS09530LWE84_RS09535
Partner old locus tags
LWE84_09530LWE84_09535
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_232915349.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE84_RS09535Primary locus identifier stored in the genes table.
Old locus tagLWE84_09535Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNS010000148.1Sequence record reported by the local genomic context database.
Genomic interval7 169-8 128 nt960 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span6 529-8 128 ntGCF_021284455::NZ_JAJSNS010000148.1::G00042

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284455::NZ_JAJSNS010000148.1::G00042

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNS010000148.1All displayed genes belong to this local TCS context.
Neighborhood span6 529-8 128 nt1 600 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 529 nt8 128 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWE84_RS09530GCF_021284455#LWE84_RS09530
RRNarL

6 529-7 176 nt · Reverse (-)

Old locus LWE84_09530RefSeq WP_009896181.1
LWE84_RS09535GCF_021284455#LWE84_RS09535
HKClassicCurrent focus

7 169-8 128 nt · Reverse (-)

Old locus LWE84_09535RefSeq WP_232915349.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2550189Run 6 · HK · 65 sequences
Representative sequenceGCF_000242355#MUI_RS0117880Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2550189

Simplified PFAM architecture for HKOC_2550189

PFAM domain coverage: 150 / 387 aa (38.8%)

1 aa387 aa
HisKA_3: 188-252 aaHisKA_3HATPase_c: 294-378 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[188-252] | HATPase_c[294-378]
  • Domain count: 2
  • Matched identifier: HKOC_2550189
  • Positioned domains: HisKA_3 188-252 ; HATPase_c 294-378
Cluster members and taxonomy
Visualization

Representative gene: GCF_000242355#MUI_RS0117880

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284455
AssemblyASM2128445v1 · Contighaploid
Genome composition4 089 563 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key