Gene detail

LWE84_RS00440

Response regulator OmpR family

Clostridioides difficile · GCF_021284455

ClassRRTypeOmpRLength223 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284455#LWE84_RS00440Stable P2CS identifier used across views.
GenomeGCF_021284455Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_1586848Run 7 · 1742 sequences · id 100% · cov 80%
External referencesWP_009897090.1 · Q187R8 · MIST4 LWE84_RS00440RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regTrans_reg_C
Protein length223 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage186 / 223 aa (83.4%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa223 aa
Response_reg: 4-112 aa (109 aa)1Trans_reg_C: 143-219 aa (77 aa)2
Domain-by-domain annotation2 items
1 Response_reg#1
4-112 aa · 109 aa · 48.9% of protein
Raw tokenResponse_reg:4:1.72e-30:112:110:111
2 Trans_reg_C#2
143-219 aa · 77 aa · 34.5% of protein
Raw tokenTrans_reg_C:143:2.77e-28:219:77:77
  • Raw architecture: Response_reg:4:1.72e-30:112:110:111#Trans_reg_C:143:2.77e-28:219:77:77
  • Domain description: 1 Response_reg,1 Trans_reg_C
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021284455::NZ_JAJSNS010000002.1::G00063
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span30488-32069Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE84_00440RefSeq proteinWP_009897090.1
Context group IDGCF_021284455::NZ_JAJSNS010000002.1::G00063
Context members
LWE84_RS00440LWE84_RS00445
Partner locus tags
LWE84_RS00440LWE84_RS00445
Partner old locus tags
LWE84_00440LWE84_00445
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009897090.1Primary protein accession used for annex mappings.
UniProt accessionQ187R8Primary UniProt accession resolved in the annex database.
UniProt IDQ187R8_CLOD6Display identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE84_RS00440Primary locus identifier stored in the genes table.
Old locus tagLWE84_00440Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNS010000002.1Sequence record reported by the local genomic context database.
Genomic interval30 488-31 159 nt672 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span30 488-32 069 ntGCF_021284455::NZ_JAJSNS010000002.1::G00063

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284455::NZ_JAJSNS010000002.1::G00063

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNS010000002.1All displayed genes belong to this local TCS context.
Neighborhood span30 488-32 069 nt1 582 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
30 488 nt32 069 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWE84_RS00440GCF_021284455#LWE84_RS00440
RROmpRCurrent focus

30 488-31 159 nt · Forward (+)

Old locus LWE84_00440RefSeq WP_009897090.1
LWE84_RS00445GCF_021284455#LWE84_RS00445
HKClassic

31 161-32 069 nt · Forward (+)

Old locus LWE84_00445RefSeq WP_016729031.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_1586848Run 7 · RR · 1742 sequences
Representative sequenceGCF_000009205#CD630_RS10600Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.

PFAM architecture for RROC_1586848

Simplified PFAM architecture for RROC_1586848

PFAM domain coverage: 185 / 223 aa (83.0%)

1 aa223 aa
Response_reg: 4-112 aaResponse_regResponse_reg: 4-112 aaResponse_regTrans_reg_C: 143-218 aaTrans_reg_CTrans_reg_C: 143-218 aaTrans_reg_C
Response_regTrans_reg_C
  • Simplified architecture: Response_reg + Trans_reg_C
  • Raw architecture: Response_reg[4-112] | Trans_reg_C[143-218]
  • Domain count: 2
  • Matched identifier: RROC_1586848
  • Positioned domains: Response_reg 4-112 ; Response_reg 4-112 ; Trans_reg_C 143-218 ; Trans_reg_C 143-218
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS10600

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284455
AssemblyASM2128445v1 · Contighaploid
Genome composition4 089 563 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key