Gene detail

LWE84_RS00425

Histidine kinase, Classic

Clostridioides difficile · GCF_021284455

ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284455#LWE84_RS00425Stable P2CS identifier used across views.
GenomeGCF_021284455Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2827844Run 6 · 131 sequences · id 100% · cov 80%
External referencesWP_016729029.1 · MIST4 LWE84_RS00425RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 343 aa (48.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa343 aa
HisKA: 124-189 aa (66 aa)1HATPase_c: 241-341 aa (101 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
124-189 aa · 66 aa · 19.2% of protein
Raw tokenHisKA:124:0.000000282:189:66:64
2 HATPase_c#2
241-341 aa · 101 aa · 29.4% of protein
Raw tokenHATPase_c:241:2.84e-24:341:101:109
  • Raw architecture: HisKA:124:0.000000282:189:66:64#HATPase_c:241:2.84e-24:341:101:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021284455::NZ_JAJSNS010000002.1::G00062
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span27297-29004Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE84_00425RefSeq proteinWP_016729029.1
Context group IDGCF_021284455::NZ_JAJSNS010000002.1::G00062
Context members
LWE84_RS00425LWE84_RS00430
Partner locus tags
LWE84_RS00425LWE84_RS00430
Partner old locus tags
LWE84_00425LWE84_00430
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_016729029.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE84_RS00425Primary locus identifier stored in the genes table.
Old locus tagLWE84_00425Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNS010000002.1Sequence record reported by the local genomic context database.
Genomic interval27 297-28 328 nt1 032 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span27 297-29 004 ntGCF_021284455::NZ_JAJSNS010000002.1::G00062

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284455::NZ_JAJSNS010000002.1::G00062

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNS010000002.1All displayed genes belong to this local TCS context.
Neighborhood span27 297-29 004 nt1 708 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
27 297 nt29 004 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWE84_RS00425GCF_021284455#LWE84_RS00425
HKClassicCurrent focus

27 297-28 328 nt · Reverse (-)

Old locus LWE84_00425RefSeq WP_016729029.1
LWE84_RS00430GCF_021284455#LWE84_RS00430
RROmpR

28 318-29 004 nt · Reverse (-)

Old locus LWE84_00430RefSeq WP_016729030.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2827844Run 6 · HK · 131 sequences
Representative sequenceGCF_000242355#MUI_RS0109615Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2827844

Simplified PFAM architecture for HKOC_2827844

PFAM domain coverage: 173 / 343 aa (50.4%)

1 aa343 aa
HisKA: 124-189 aaHisKAHATPase_c: 236-342 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[124-189] | HATPase_c[236-342]
  • Domain count: 2
  • Matched identifier: HKOC_2827844
  • Positioned domains: HisKA 124-189 ; HATPase_c 236-342
Cluster members and taxonomy
Visualization

Representative gene: GCF_000242355#MUI_RS0109615

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284455
AssemblyASM2128445v1 · Contighaploid
Genome composition4 089 563 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key