Gene detail

LWE84_RS00020

Histidine kinase, Classic

Clostridioides difficile · GCF_021284455

ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284455#LWE84_RS00020Stable P2CS identifier used across views.
GenomeGCF_021284455Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2829451Run 6 · 12 sequences · id 100% · cov 80%
External referencesWP_004611601.1 · MIST4 LWE84_RS00020RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 343 aa (49.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa343 aa
HisKA: 123-189 aa (67 aa)1HATPase_c: 241-341 aa (101 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
123-189 aa · 67 aa · 19.5% of protein
Raw tokenHisKA:123:0.00000012:189:67:64
2 HATPase_c#2
241-341 aa · 101 aa · 29.4% of protein
Raw tokenHATPase_c:241:9.42e-28:341:101:109
  • Raw architecture: HisKA:123:0.00000012:189:67:64#HATPase_c:241:9.42e-28:341:101:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021284455::NZ_JAJSNS010000001.1::G00044
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4340-6060Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE84_00020RefSeq proteinWP_004611601.1
Context group IDGCF_021284455::NZ_JAJSNS010000001.1::G00044
Context members
LWE84_RS00020LWE84_RS00025
Partner locus tags
LWE84_RS00020LWE84_RS00025
Partner old locus tags
LWE84_00020LWE84_00025
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_004611601.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE84_RS00020Primary locus identifier stored in the genes table.
Old locus tagLWE84_00020Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNS010000001.1Sequence record reported by the local genomic context database.
Genomic interval4 340-5 371 nt1 032 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 340-6 060 ntGCF_021284455::NZ_JAJSNS010000001.1::G00044

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284455::NZ_JAJSNS010000001.1::G00044

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNS010000001.1All displayed genes belong to this local TCS context.
Neighborhood span4 340-6 060 nt1 721 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 340 nt6 060 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWE84_RS00020GCF_021284455#LWE84_RS00020
HKClassicCurrent focus

4 340-5 371 nt · Reverse (-)

Old locus LWE84_00020RefSeq WP_004611601.1
LWE84_RS00025GCF_021284455#LWE84_RS00025
RROmpR

5 368-6 060 nt · Reverse (-)

Old locus LWE84_00025RefSeq WP_021632060.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2829451Run 6 · HK · 12 sequences
Representative sequenceGCF_013299755#G4366_RS10215Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2829451

Simplified PFAM architecture for HKOC_2829451

PFAM domain coverage: 174 / 343 aa (50.7%)

1 aa343 aa
HisKA: 124-189 aaHisKAHATPase_c: 235-342 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[124-189] | HATPase_c[235-342]
  • Domain count: 2
  • Matched identifier: HKOC_2829451
  • Positioned domains: HisKA 124-189 ; HATPase_c 235-342
Cluster members and taxonomy
Visualization

Representative gene: GCF_013299755#G4366_RS10215

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 12 over 12 total members. Page 1 / 1.

GCF_013299755#G4366_RS10215 (representative)
G4366_RS10215 · HK · Classic
RefSeq: WP_004611601.1
GCF_013300745#G4350_RS09915
G4350_RS09915 · HK · Classic
RefSeq: WP_004611601.1
GCF_013301465#G4388_RS09830
G4388_RS09830 · HK · Classic
RefSeq: WP_004611601.1
GCF_013301475#G4393_RS10470
G4393_RS10470 · HK · Classic
RefSeq: WP_004611601.1
GCF_013301515#G4360_RS10085
G4360_RS10085 · HK · Classic
RefSeq: WP_004611601.1
GCF_013301525#G4478_RS09980
G4478_RS09980 · HK · Classic
RefSeq: WP_004611601.1
GCF_013302125#G5A00_RS06570
G5A00_RS06570 · HK · Classic
RefSeq: WP_004611601.1
GCF_021284455#LWE84_RS00020
LWE84_RS00020 · HK · Classic
RefSeq: WP_004611601.1
GCF_021284485#LWE75_RS00265
LWE75_RS00265 · HK · Classic
RefSeq: WP_004611601.1
GCF_021284495#LWF07_RS00285
LWF07_RS00285 · HK · Classic
RefSeq: WP_004611601.1
GCF_021284615#LWF05_RS00265
LWF05_RS00265 · HK · Classic
RefSeq: WP_004611601.1
GCF_900104635#BQ5364_RS11425
BQ5364_RS11425 · HK · Classic
RefSeq: WP_004611601.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284455
AssemblyASM2128445v1 · Contighaploid
Genome composition4 089 563 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key