Gene detail

LWE80_RS16325

Histidine kinase, Classic

Clostridioides difficile · GCF_021284445

ClassHKTypeClassicLength912 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_021284445#LWE80_RS16325Stable P2CS identifier used across views.
GenomeGCF_021284445Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0387916Run 6 · 10 sequences · id 100% · cov 80%
External referencesWP_022615985.1 · MIST4 LWE80_RS16325RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_8HisKAHATPase_c
Protein length912 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage222 / 912 aa (24.3%)Merged over positioned domains only.
Domain description1 PAS_8,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa912 aa
PAS_8: 532-569 aa (38 aa)1HisKA: 655-726 aa (72 aa)2HATPase_c: 774-885 aa (112 aa)3
Domain-by-domain annotation3 items
1 PAS_8#1
532-569 aa · 38 aa · 4.2% of protein
Raw tokenPAS_8:532:0.0000841:569:38:65
2 HisKA#2
655-726 aa · 72 aa · 7.9% of protein
Raw tokenHisKA:655:0.00000000531:726:72:64
3 HATPase_c#3
774-885 aa · 112 aa · 12.3% of protein
Raw tokenHATPase_c:774:1.89e-24:885:112:109
  • Raw architecture: PAS_8:532:0.0000841:569:38:65#HisKA:655:0.00000000531:726:72:64#HATPase_c:774:1.89e-24:885:112:109
  • Domain description: 1 PAS_8,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_021284445::NZ_JAJSOC010000191.1::G00046
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span2899-5637Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE80_16285RefSeq proteinWP_022615985.1
Context group IDGCF_021284445::NZ_JAJSOC010000191.1::G00046
Context members
LWE80_RS16325
Partner locus tags
LWE80_RS16325
Partner old locus tags
LWE80_16285
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_022615985.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE80_RS16325Primary locus identifier stored in the genes table.
Old locus tagLWE80_16285Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSOC010000191.1Sequence record reported by the local genomic context database.
Genomic interval2 899-5 637 nt2 739 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 899-5 637 ntGCF_021284445::NZ_JAJSOC010000191.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284445::NZ_JAJSOC010000191.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSOC010000191.1All displayed genes belong to this local TCS context.
Neighborhood span2 899-5 637 nt2 739 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 899 nt5 637 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

LWE80_RS16325GCF_021284445#LWE80_RS16325
HKClassicCurrent focus

2 899-5 637 nt · Forward (+)

Old locus LWE80_16285RefSeq WP_022615985.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0387916Run 6 · HK · 10 sequences
Representative sequenceGCF_000531165#BN166_RS10180Use this link to inspect the representative gene detail.
PFAM architecturePAS_8 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0387916

Simplified PFAM architecture for HKOC_0387916

PFAM domain coverage: 221 / 912 aa (24.2%)

1 aa912 aa
PAS_8: 532-572 aaHisKA: 656-724 aaHisKAHATPase_c: 774-884 aaHATPase_c
PAS_8HisKAHATPase_c
  • Simplified architecture: PAS_8 + HisKA + HATPase_c
  • Raw architecture: PAS_8[532-572] | HisKA[656-724] | HATPase_c[774-884]
  • Domain count: 3
  • Matched identifier: HKOC_0387916
  • Positioned domains: PAS_8 532-572 ; HisKA 656-724 ; HATPase_c 774-884
Cluster members and taxonomy
Visualization

Representative gene: GCF_000531165#BN166_RS10180

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284445
AssemblyASM2128444v1 · Contighaploid
Genome composition3 956 132 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key