Gene detail

LWE80_RS07300

Histidine kinase, Classic

Clostridioides difficile · GCF_021284445

ClassHKTypeClassicLength345 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284445#LWE80_RS07300Stable P2CS identifier used across views.
GenomeGCF_021284445Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2819252Run 6 · 10 sequences · id 100% · cov 80%
External referencesWP_032554265.1 · MIST4 LWE80_RS07300RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length345 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 345 aa (49.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa345 aa
HisKA: 123-188 aa (66 aa)1HATPase_c: 234-337 aa (104 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
123-188 aa · 66 aa · 19.1% of protein
Raw tokenHisKA:123:0.00000000157:188:66:64
2 HATPase_c#2
234-337 aa · 104 aa · 30.1% of protein
Raw tokenHATPase_c:234:5.1e-28:337:104:109
  • Raw architecture: HisKA:123:0.00000000157:188:66:64#HATPase_c:234:5.1e-28:337:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021284445::NZ_JAJSOC010000046.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span7544-9276Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE80_07290RefSeq proteinWP_032554265.1
Context group IDGCF_021284445::NZ_JAJSOC010000046.1::G00005
Context members
LWE80_RS07300LWE80_RS07305
Partner locus tags
LWE80_RS07300LWE80_RS07305
Partner old locus tags
LWE80_07290LWE80_07295
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_032554265.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE80_RS07300Primary locus identifier stored in the genes table.
Old locus tagLWE80_07290Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSOC010000046.1Sequence record reported by the local genomic context database.
Genomic interval7 544-8 581 nt1 038 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span7 544-9 276 ntGCF_021284445::NZ_JAJSOC010000046.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284445::NZ_JAJSOC010000046.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSOC010000046.1All displayed genes belong to this local TCS context.
Neighborhood span7 544-9 276 nt1 733 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
7 544 nt9 276 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWE80_RS07300GCF_021284445#LWE80_RS07300
HKClassicCurrent focus

7 544-8 581 nt · Reverse (-)

Old locus LWE80_07290RefSeq WP_032554265.1
LWE80_RS07305GCF_021284445#LWE80_RS07305
RROmpR

8 590-9 276 nt · Reverse (-)

Old locus LWE80_07295RefSeq WP_022616332.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2819252Run 6 · HK · 10 sequences
Representative sequenceGCF_000531165#BN166_RS00120Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2819252

Simplified PFAM architecture for HKOC_2819252

PFAM domain coverage: 171 / 345 aa (49.6%)

1 aa345 aa
HisKA: 124-188 aaHisKAHATPase_c: 234-339 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[124-188] | HATPase_c[234-339]
  • Domain count: 2
  • Matched identifier: HKOC_2819252
  • Positioned domains: HisKA 124-188 ; HATPase_c 234-339
Cluster members and taxonomy
Visualization

Representative gene: GCF_000531165#BN166_RS00120

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284445
AssemblyASM2128444v1 · Contighaploid
Genome composition3 956 132 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key