Gene detail

LWE80_RS03755

Histidine kinase, Classic

Clostridioides difficile · GCF_021284445

ClassHKTypeClassicLength690 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284445#LWE80_RS03755Stable P2CS identifier used across views.
GenomeGCF_021284445Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0791101Run 6 · 13 sequences · id 100% · cov 80%
External referencesWP_022616104.1 · MIST4 LWE80_RS03755RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length690 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 690 aa (23.5%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa690 aa
HisKA: 457-524 aa (68 aa)1HATPase_c: 570-663 aa (94 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
457-524 aa · 68 aa · 9.9% of protein
Raw tokenHisKA:457:0.0000000000000274:524:68:64
2 HATPase_c#2
570-663 aa · 94 aa · 13.6% of protein
Raw tokenHATPase_c:570:0.000000000000783:663:98:109
  • Raw architecture: HisKA:457:0.0000000000000274:524:68:64#HATPase_c:570:0.000000000000783:663:98:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021284445::NZ_JAJSOC010000020.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2642-5602Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE80_03750RefSeq proteinWP_022616104.1
Context group IDGCF_021284445::NZ_JAJSOC010000020.1::G00013
Context members
LWE80_RS03750LWE80_RS03755
Partner locus tags
LWE80_RS03750LWE80_RS03755
Partner old locus tags
LWE80_03745LWE80_03750
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_022616104.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE80_RS03755Primary locus identifier stored in the genes table.
Old locus tagLWE80_03750Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSOC010000020.1Sequence record reported by the local genomic context database.
Genomic interval3 530-5 602 nt2 073 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 642-5 602 ntGCF_021284445::NZ_JAJSOC010000020.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284445::NZ_JAJSOC010000020.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSOC010000020.1All displayed genes belong to this local TCS context.
Neighborhood span2 642-5 602 nt2 961 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 642 nt5 602 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWE80_RS03750GCF_021284445#LWE80_RS03750
RROmpR

2 642-3 334 nt · Forward (+)

Old locus LWE80_03745RefSeq WP_003423181.1
LWE80_RS03755GCF_021284445#LWE80_RS03755
HKClassicCurrent focus

3 530-5 602 nt · Forward (+)

Old locus LWE80_03750RefSeq WP_022616104.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0791101Run 6 · HK · 13 sequences
Representative sequenceGCF_000531165#BN166_RS06485Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0791101

Simplified PFAM architecture for HKOC_0791101

PFAM domain coverage: 160 / 690 aa (23.2%)

1 aa690 aa
HisKA: 457-524 aaHisKAHATPase_c: 571-662 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[457-524] | HATPase_c[571-662]
  • Domain count: 2
  • Matched identifier: HKOC_0791101
  • Positioned domains: HisKA 457-524 ; HATPase_c 571-662
Cluster members and taxonomy
Visualization

Representative gene: GCF_000531165#BN166_RS06485

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284445
AssemblyASM2128444v1 · Contighaploid
Genome composition3 956 132 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key