1 HAMP#1
121-188 aa · 68 aa · 16.4% of protein
Raw token
HAMP:121:0.00000000000415:188:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWE99_RS17275
Histidine kinase, Classic
Clostridioides difficile · GCF_021284405
ClassHKTypeClassicLength415 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_021284405#LWE99_RS17275Stable P2CS identifier used across views.
GenomeGCF_021284405Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length415 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage213 / 415 aa (51.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa415 aa
Domain-by-domain annotation3 items
2 HisKA#2
200-259 aa · 60 aa · 14.5% of protein
Raw token
HisKA:200:0.000000000199:259:61:643 HATPase_c#3
306-390 aa · 85 aa · 20.5% of protein
Raw token
HATPase_c:306:0.00000000000000112:390:88:109- Raw architecture: HAMP:121:0.00000000000415:188:68:69#HisKA:200:0.000000000199:259:61:64#HATPase_c:306:0.00000000000000112:390:88:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_021284405::NZ_JAJSNZ010000245.1::G00016
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-1249Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE99_17300RefSeq proteinWP_232872220.1
Context group ID
GCF_021284405::NZ_JAJSNZ010000245.1::G00016Context members
LWE99_RS17275
Partner locus tags
LWE99_RS17275
Partner old locus tags
LWE99_17300
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_232872220.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWE99_RS17275Primary locus identifier stored in the genes table.
Old locus tagLWE99_17300Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNZ010000245.1Sequence record reported by the local genomic context database.
Genomic interval1-1 249 nt1 249 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-1 249 ntGCF_021284405::NZ_JAJSNZ010000245.1::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_021284405::NZ_JAJSNZ010000245.1::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNZ010000245.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 249 nt1 249 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 249 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
LWE99_RS17275GCF_021284405#LWE99_RS17275
HKClassicCurrent focus
1-1 249 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0202465Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1783726
Simplified PFAM architecture for HKOC_1783726
PFAM domain coverage: 195 / 464 aa (42.0%)
1 aa464 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[187-236] | HisKA[250-308] | HATPase_c[355-440]
- Domain count: 3
- Matched identifier: HKOC_1783726
- Positioned domains: HAMP 187-236 ; HisKA 250-308 ; HATPase_c 355-440
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0202465
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284405
AssemblyASM2128440v1 · Contighaploid
Genome composition3 958 330 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key