Gene detail

LWE97_RS11660

Histidine kinase, CheA

Clostridioides difficile · GCF_021284345

ClassHKTypeCheALength435 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_021284345#LWE97_RS11660Stable P2CS identifier used across views.
GenomeGCF_021284345Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0768912Run 6 · 527 sequences · id 100% · cov 80%
External referencesWP_232887585.1 · MIST4 LWE97_RS11660RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

H-kinase_dimHATPase_cCheW
Protein length435 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage337 / 435 aa (77.5%)Merged over positioned domains only.
Domain description1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa435 aa
H-kinase_dim: 47-108 aa (62 aa)1HATPase_c: 155-294 aa (140 aa)2CheW: 299-433 aa (135 aa)3
Domain-by-domain annotation3 items
1 H-kinase_dim#1
47-108 aa · 62 aa · 14.3% of protein
Raw tokenH-kinase_dim:47:0.00000000000000366:108:67:67
2 HATPase_c#2
155-294 aa · 140 aa · 32.2% of protein
Raw tokenHATPase_c:155:7.18e-17:294:140:109
3 CheW#3
299-433 aa · 135 aa · 31.0% of protein
Raw tokenCheW:299:5.07e-22:433:136:138
  • Raw architecture: H-kinase_dim:47:0.00000000000000366:108:67:67#HATPase_c:155:7.18e-17:294:140:109#CheW:299:5.07e-22:433:136:138
  • Domain description: 1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_021284345::NZ_JAJSNO010000231.1::G00032
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-1309Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE97_11680RefSeq proteinWP_232887585.1
Context group IDGCF_021284345::NZ_JAJSNO010000231.1::G00032
Context members
LWE97_RS11660
Partner locus tags
LWE97_RS11660
Partner old locus tags
LWE97_11680
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_232887585.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE97_RS11660Primary locus identifier stored in the genes table.
Old locus tagLWE97_11680Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNO010000231.1Sequence record reported by the local genomic context database.
Genomic interval1-1 309 nt1 309 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-1 309 ntGCF_021284345::NZ_JAJSNO010000231.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284345::NZ_JAJSNO010000231.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNO010000231.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 309 nt1 309 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 309 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0768912Run 6 · HK · 527 sequences
Representative sequenceGCF_000009205#CD630_RS03265Use this link to inspect the representative gene detail.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0768912

Simplified PFAM architecture for HKOC_0768912

PFAM domain coverage: 513 / 700 aa (73.3%)

1 aa700 aa
Hpt: 3-104 aaHptP2: 164-240 aaP2H-kinase_dim: 312-373 aaH-kinase_dimHATPase_c: 422-559 aaHATPase_cCheW: 565-698 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[3-104] | P2[164-240] | H-kinase_dim[312-373] | HATPase_c[422-559] | CheW[565-698]
  • Domain count: 5
  • Matched identifier: HKOC_0768912
  • Positioned domains: Hpt 3-104 ; P2 164-240 ; H-kinase_dim 312-373 ; HATPase_c 422-559 ; CheW 565-698
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS03265

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284345
AssemblyASM2128434v1 · Contighaploid
Genome composition4 244 082 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 50 · RR 53CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key