Gene detail

LWF11_RS01685

Histidine kinase, Classic

Clostridioides difficile · GCF_021284275

ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284275#LWF11_RS01685Stable P2CS identifier used across views.
GenomeGCF_021284275Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2881988Run 6 · 241 sequences · id 100% · cov 80%
External referencesWP_011861096.1 · A0A4P9CFA0 · MIST4 LWF11_RS01685RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 305 aa (57.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for LWF11_RS01685
Domain-by-domain annotation2 items
1 HisKA#1
85-150 aa · 66 aa · 21.6% of protein
Raw tokenHisKA:85:0.0000000591:150:66:64
2 HATPase_c#2
197-305 aa · 109 aa · 35.7% of protein
Raw tokenHATPase_c:197:4.48e-31:305:109:109
  • Raw architecture: HisKA:85:0.0000000591:150:66:64#HATPase_c:197:4.48e-31:305:109:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021284275::NZ_JAJSNK010000018.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span13760-15376Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWF11_01680RefSeq proteinWP_011861096.1
Context group IDGCF_021284275::NZ_JAJSNK010000018.1::G00002
Context members
LWF11_RS01685LWF11_RS01690
Partner locus tags
LWF11_RS01685LWF11_RS01690
Partner old locus tags
LWF11_01680LWF11_01685
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_011861096.1Primary protein accession used for annex mappings.
UniProt accessionA0A4P9CFA0Primary UniProt accession resolved in the annex database.
UniProt IDA0A4P9CFA0_EUBMLDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWF11_RS01685Primary locus identifier stored in the genes table.
Old locus tagLWF11_01680Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNK010000018.1Sequence record reported by the local genomic context database.
Genomic interval13 760-14 677 nt918 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span13 760-15 376 ntGCF_021284275::NZ_JAJSNK010000018.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284275::NZ_JAJSNK010000018.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNK010000018.1All displayed genes belong to this local TCS context.
Neighborhood span13 760-15 376 nt1 617 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
13 760 nt15 376 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWF11_RS01685GCF_021284275#LWF11_RS01685
HKClassicCurrent focus

13 760-14 677 nt · Reverse (-)

Old locus LWF11_01680RefSeq WP_011861096.1
LWF11_RS01690GCF_021284275#LWF11_RS01690
RROmpR

14 684-15 376 nt · Reverse (-)

Old locus LWF11_01685RefSeq WP_016728879.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2881988Run 6 · HK · 241 sequences
Representative sequenceGCF_000009205#CD630_RS06130Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2881988

Simplified PFAM architecture for HKOC_2881988

PFAM domain coverage: 172 / 305 aa (56.4%)

1 aa305 aa
HisKA: 85-148 aaHisKAHATPase_c: 197-304 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[85-148] | HATPase_c[197-304]
  • Domain count: 2
  • Matched identifier: HKOC_2881988
  • Positioned domains: HisKA 85-148 ; HATPase_c 197-304
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS06130

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284275
AssemblyASM2128427v1 · Contighaploid
Genome composition4 238 945 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 53CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key