1 HisKA#1
230-293 aa · 64 aa · 14.0% of protein
Raw token
HisKA:230:0.00000000000173:293:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWE72_RS00130
Histidine kinase, Classic
Clostridioides difficile · GCF_021284185
ClassHKTypeClassicLength456 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284185#LWE72_RS00130Stable P2CS identifier used across views.
GenomeGCF_021284185Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length456 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage177 / 456 aa (38.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa456 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
343-455 aa · 113 aa · 24.8% of protein
Raw token
HATPase_c:343:6.29e-22:455:113:109- Raw architecture: HisKA:230:0.00000000000173:293:64:64#HATPase_c:343:6.29e-22:455:113:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_021284185::NZ_JAJSMX010000001.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span21615-23677Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE72_00130RefSeq proteinWP_009901661.1
Context group ID
GCF_021284185::NZ_JAJSMX010000001.1::G00032Context members
LWE72_RS00130LWE72_RS00135
Partner locus tags
LWE72_RS00130LWE72_RS00135
Partner old locus tags
LWE72_00130LWE72_00135
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009901661.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QD75Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QD75_CLODIDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWE72_RS00130Primary locus identifier stored in the genes table.
Old locus tagLWE72_00130Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSMX010000001.1Sequence record reported by the local genomic context database.
Genomic interval21 615-22 985 nt1 371 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span21 615-23 677 ntGCF_021284185::NZ_JAJSMX010000001.1::G00032
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_021284185::NZ_JAJSMX010000001.1::G00032Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSMX010000001.1All displayed genes belong to this local TCS context.
Neighborhood span21 615-23 677 nt2 063 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
21 615 nt23 677 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
LWE72_RS00130GCF_021284185#LWE72_RS00130
HKClassicCurrent focus
21 615-22 985 nt · Reverse (-)
LWE72_RS00135GCF_021284185#LWE72_RS00135
RROmpR
22 982-23 677 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155025#UAB_RS0201840Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1887710
Simplified PFAM architecture for HKOC_1887710
PFAM domain coverage: 176 / 456 aa (38.6%)
1 aa456 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[230-293] | HATPase_c[343-454]
- Domain count: 2
- Matched identifier: HKOC_1887710
- Positioned domains: HisKA 230-293 ; HATPase_c 343-454
Cluster members and taxonomy
Representative gene: GCF_000155025#UAB_RS0201840
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284185
AssemblyASM2128418v1 · Contighaploid
Genome composition4 200 715 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 45 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key