Gene detail

LWE83_RS02020

Histidine kinase, Classic

Clostridioides difficile · GCF_021284065

ClassHKTypeClassicLength912 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_021284065#LWE83_RS02020Stable P2CS identifier used across views.
GenomeGCF_021284065Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0387826Run 6 · 268 sequences · id 100% · cov 80%
External referencesWP_003416499.1 · D5Q2F2 · MIST4 LWE83_RS02020RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

MASE3PAS_9HisKAHATPase_c
Protein length912 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage499 / 912 aa (54.7%)Merged over positioned domains only.
Domain description1 MASE3,1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa912 aa
MASE3: 43-257 aa (215 aa)1PAS_9: 529-629 aa (101 aa)2HisKA: 655-726 aa (72 aa)3HATPase_c: 773-883 aa (111 aa)4
Domain-by-domain annotation4 items
1 MASE3#1
43-257 aa · 215 aa · 23.6% of protein
Raw tokenMASE3:43:0.000048:257:227:226
2 PAS_9#2
529-629 aa · 101 aa · 11.1% of protein
Raw tokenPAS_9:529:0.0000503:629:101:102
3 HisKA#3
655-726 aa · 72 aa · 7.9% of protein
Raw tokenHisKA:655:0.0000000000000106:726:72:64
4 HATPase_c#4
773-883 aa · 111 aa · 12.2% of protein
Raw tokenHATPase_c:773:4.7e-31:883:111:109
  • Raw architecture: MASE3:43:0.000048:257:227:226#PAS_9:529:0.0000503:629:101:102#HisKA:655:0.0000000000000106:726:72:64#HATPase_c:773:4.7e-31:883:111:109
  • Domain description: 1 MASE3,1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_021284065::NZ_JAJSNL010000016.1::G00053
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span10083-12821Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE83_02020RefSeq proteinWP_003416499.1
Context group IDGCF_021284065::NZ_JAJSNL010000016.1::G00053
Context members
LWE83_RS02020
Partner locus tags
LWE83_RS02020
Partner old locus tags
LWE83_02020
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003416499.1Primary protein accession used for annex mappings.
UniProt accessionD5Q2F2Primary UniProt accession resolved in the annex database.
UniProt IDD5Q2F2_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE83_RS02020Primary locus identifier stored in the genes table.
Old locus tagLWE83_02020Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNL010000016.1Sequence record reported by the local genomic context database.
Genomic interval10 083-12 821 nt2 739 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span10 083-12 821 ntGCF_021284065::NZ_JAJSNL010000016.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284065::NZ_JAJSNL010000016.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNL010000016.1All displayed genes belong to this local TCS context.
Neighborhood span10 083-12 821 nt2 739 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
10 083 nt12 821 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

LWE83_RS02020GCF_021284065#LWE83_RS02020
HKClassicCurrent focus

10 083-12 821 nt · Reverse (-)

Old locus LWE83_02020RefSeq WP_003416499.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0387826Run 6 · HK · 268 sequences
Representative sequenceGCF_000164175#HMPREF0220_RS17020Use this link to inspect the representative gene detail.
PFAM architecturePAS_8 + PAS_9 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0387826

Simplified PFAM architecture for HKOC_0387826

PFAM domain coverage: 341 / 912 aa (37.4%)

1 aa912 aa
PAS_8: 303-356 aaPAS_8PAS_9: 529-632 aaPAS_9HisKA: 655-726 aaHisKAHATPase_c: 773-883 aaHATPase_c
PAS_8PAS_9HisKAHATPase_c
  • Simplified architecture: PAS_8 + PAS_9 + HisKA + HATPase_c
  • Raw architecture: PAS_8[303-356] | PAS_9[529-632] | HisKA[655-726] | HATPase_c[773-883]
  • Domain count: 4
  • Matched identifier: HKOC_0387826
  • Positioned domains: PAS_8 303-356 ; PAS_9 529-632 ; HisKA 655-726 ; HATPase_c 773-883
Cluster members and taxonomy
Visualization

Representative gene: GCF_000164175#HMPREF0220_RS17020

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284065
AssemblyASM2128406v1 · Contighaploid
Genome composition3 893 154 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 95 · HK 46 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key