Gene detail

LWE88_RS08230

Histidine kinase, Classic

Clostridioides difficile · GCF_021284005

ClassHKTypeClassicLength374 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_021284005#LWE88_RS08230Stable P2CS identifier used across views.
GenomeGCF_021284005Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1355675Run 6 · 96 sequences · id 100% · cov 80%
External referencesWP_232879401.1 · MIST4 LWE88_RS08230RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length374 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 374 aa (40.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa374 aa
HisKA: 153-219 aa (67 aa)1HATPase_c: 272-357 aa (86 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
153-219 aa · 67 aa · 17.9% of protein
Raw tokenHisKA:153:0.0000000000000116:219:67:64
2 HATPase_c#2
272-357 aa · 86 aa · 23.0% of protein
Raw tokenHATPase_c:272:0.0000000416:357:90:109
  • Raw architecture: HisKA:153:0.0000000000000116:219:67:64#HATPase_c:272:0.0000000416:357:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_021284005::NZ_JAJSMU010000109.1::G00003
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span8909-10034Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE88_08215RefSeq proteinWP_232879401.1
Context group IDGCF_021284005::NZ_JAJSMU010000109.1::G00003
Context members
LWE88_RS08230
Partner locus tags
LWE88_RS08230
Partner old locus tags
LWE88_08215
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_232879401.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE88_RS08230Primary locus identifier stored in the genes table.
Old locus tagLWE88_08215Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSMU010000109.1Sequence record reported by the local genomic context database.
Genomic interval8 909-10 034 nt1 126 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span8 909-10 034 ntGCF_021284005::NZ_JAJSMU010000109.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284005::NZ_JAJSMU010000109.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSMU010000109.1All displayed genes belong to this local TCS context.
Neighborhood span8 909-10 034 nt1 126 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 909 nt10 034 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

LWE88_RS08230GCF_021284005#LWE88_RS08230
HKClassicCurrent focus

8 909-10 034 nt · Reverse (-)

Old locus LWE88_08215RefSeq WP_232879401.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1355675Run 6 · HK · 96 sequences
Representative sequenceGCF_000448765#QC5_RS11670Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1355675

Simplified PFAM architecture for HKOC_1355675

PFAM domain coverage: 191 / 530 aa (36.0%)

1 aa530 aa
HAMP: 255-295 aaHAMPHisKA: 310-375 aaHisKAHATPase_c: 427-510 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[255-295] | HisKA[310-375] | HATPase_c[427-510]
  • Domain count: 3
  • Matched identifier: HKOC_1355675
  • Positioned domains: HAMP 255-295 ; HisKA 310-375 ; HATPase_c 427-510
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS11670

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284005
AssemblyASM2128400v1 · Contighaploid
Genome composition3 973 955 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key