1 HAMP#1
117-184 aa · 68 aa · 16.5% of protein
Raw token
HAMP:117:0.00000000000488:184:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWE86_RS18145
Histidine kinase, Classic
Clostridioides difficile · GCF_021283885
ClassHKTypeClassicLength413 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_021283885#LWE86_RS18145Stable P2CS identifier used across views.
GenomeGCF_021283885Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length413 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage213 / 413 aa (51.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa413 aa
Domain-by-domain annotation3 items
2 HisKA#2
196-255 aa · 60 aa · 14.5% of protein
Raw token
HisKA:196:0.000000000222:255:61:643 HATPase_c#3
302-386 aa · 85 aa · 20.6% of protein
Raw token
HATPase_c:302:0.00000000000000109:386:88:109- Raw architecture: HAMP:117:0.00000000000488:184:68:69#HisKA:196:0.000000000222:255:61:64#HATPase_c:302:0.00000000000000109:386:88:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_021283885::NZ_JAJSNY010000321.1::G00023
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-1238Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE86_18145RefSeq proteinWP_232897001.1
Context group ID
GCF_021283885::NZ_JAJSNY010000321.1::G00023Context members
LWE86_RS18145
Partner locus tags
LWE86_RS18145
Partner old locus tags
LWE86_18145
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_232897001.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWE86_RS18145Primary locus identifier stored in the genes table.
Old locus tagLWE86_18145Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNY010000321.1Sequence record reported by the local genomic context database.
Genomic interval1-1 238 nt1 238 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1-1 238 ntGCF_021283885::NZ_JAJSNY010000321.1::G00023
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_021283885::NZ_JAJSNY010000321.1::G00023Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNY010000321.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 238 nt1 238 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 238 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
LWE86_RS18145GCF_021283885#LWE86_RS18145
HKClassicCurrent focus
1-1 238 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_021283885#LWE86_RS18145The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2331439
Simplified PFAM architecture for HKOC_2331439
PFAM domain coverage: 195 / 413 aa (47.2%)
1 aa413 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[134-183] | HisKA[197-255] | HATPase_c[302-387]
- Domain count: 3
- Matched identifier: HKOC_2331439
- Positioned domains: HAMP 134-183 ; HisKA 197-255 ; HATPase_c 302-387
Cluster members and taxonomy
Representative gene: GCF_021283885#LWE86_RS18145
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283885
AssemblyASM2128388v1 · Contighaploid
Genome composition3 962 467 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key