Gene detail

LWF00_RS00280

Histidine kinase, Classic

Clostridioides difficile · GCF_021283865

ClassHKTypeClassicLength302 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021283865#LWF00_RS00280Stable P2CS identifier used across views.
GenomeGCF_021283865Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2883605Run 6 · 237 sequences · id 100% · cov 80%
External referencesWP_016729031.1 · MIST4 LWF00_RS00280RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length302 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage163 / 302 aa (54.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa302 aa
HisKA: 82-144 aa (63 aa)1HATPase_c: 196-295 aa (100 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
82-144 aa · 63 aa · 20.9% of protein
Raw tokenHisKA:82:0.000000074:144:63:64
2 HATPase_c#2
196-295 aa · 100 aa · 33.1% of protein
Raw tokenHATPase_c:196:2.14e-22:295:100:109
  • Raw architecture: HisKA:82:0.000000074:144:63:64#HATPase_c:196:2.14e-22:295:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021283865::NZ_JAJSNE010000002.1::G00056
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span28390-29971Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWF00_00275RefSeq proteinWP_016729031.1
Context group IDGCF_021283865::NZ_JAJSNE010000002.1::G00056
Context members
LWF00_RS00275LWF00_RS00280
Partner locus tags
LWF00_RS00275LWF00_RS00280
Partner old locus tags
LWF00_00270LWF00_00275
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_016729031.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWF00_RS00280Primary locus identifier stored in the genes table.
Old locus tagLWF00_00275Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNE010000002.1Sequence record reported by the local genomic context database.
Genomic interval29 063-29 971 nt909 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span28 390-29 971 ntGCF_021283865::NZ_JAJSNE010000002.1::G00056

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021283865::NZ_JAJSNE010000002.1::G00056

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNE010000002.1All displayed genes belong to this local TCS context.
Neighborhood span28 390-29 971 nt1 582 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
28 390 nt29 971 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWF00_RS00275GCF_021283865#LWF00_RS00275
RROmpR

28 390-29 061 nt · Forward (+)

Old locus LWF00_00270RefSeq WP_009897090.1
LWF00_RS00280GCF_021283865#LWF00_RS00280
HKClassicCurrent focus

29 063-29 971 nt · Forward (+)

Old locus LWF00_00275RefSeq WP_016729031.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2883605Run 6 · HK · 237 sequences
Representative sequenceGCF_034188235#SQ514_RS09400Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2883605

Simplified PFAM architecture for HKOC_2883605

PFAM domain coverage: 165 / 304 aa (54.3%)

1 aa304 aa
HisKA: 84-146 aaHisKAHATPase_c: 197-298 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[84-146] | HATPase_c[197-298]
  • Domain count: 2
  • Matched identifier: HKOC_2883605
  • Positioned domains: HisKA 84-146 ; HATPase_c 197-298
Cluster members and taxonomy
Visualization

Representative gene: GCF_034188235#SQ514_RS09400

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283865
AssemblyASM2128386v1 · Contighaploid
Genome composition4 099 090 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 49 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key