1 H-kinase_dim#1
56-117 aa · 62 aa · 14.0% of protein
Raw token
H-kinase_dim:56:0.00000000000000383:117:67:67P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWG76_RS12215
Histidine kinase, CheA
Clostridioides difficile · GCF_021283845
ClassHKTypeCheALength444 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_021283845#LWG76_RS12215Stable P2CS identifier used across views.
GenomeGCF_021283845Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
H-kinase_dimHATPase_cCheW
Protein length444 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage336 / 444 aa (75.7%)Merged over positioned domains only.
Domain description1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa444 aa
Domain-by-domain annotation3 items
2 HATPase_c#2
165-303 aa · 139 aa · 31.3% of protein
Raw token
HATPase_c:165:1.29e-17:303:139:1093 CheW#3
308-442 aa · 135 aa · 30.4% of protein
Raw token
CheW:308:3.83e-22:442:136:138- Raw architecture: H-kinase_dim:56:0.00000000000000383:117:67:67#HATPase_c:165:1.29e-17:303:139:109#CheW:308:3.83e-22:442:136:138
- Domain description: 1 H-kinase_dim,1 HATPase_c,1 CheW
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_021283845::NZ_JAJSMJ010000231.1::G00054
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span4782-6117Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWG76_12205RefSeq proteinWP_232918325.1
Context group ID
GCF_021283845::NZ_JAJSMJ010000231.1::G00054Context members
LWG76_RS12215
Partner locus tags
LWG76_RS12215
Partner old locus tags
LWG76_12205
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_232918325.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWG76_RS12215Primary locus identifier stored in the genes table.
Old locus tagLWG76_12205Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSMJ010000231.1Sequence record reported by the local genomic context database.
Genomic interval4 782-6 117 nt1 336 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 782-6 117 ntGCF_021283845::NZ_JAJSMJ010000231.1::G00054
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_021283845::NZ_JAJSMJ010000231.1::G00054Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSMJ010000231.1All displayed genes belong to this local TCS context.
Neighborhood span4 782-6 117 nt1 336 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 782 nt6 117 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
LWG76_RS12215GCF_021283845#LWG76_RS12215
HKCheACurrent focus
4 782-6 117 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000164175#HMPREF0220_RS08600Use this link to inspect the representative gene detail.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0768948
Simplified PFAM architecture for HKOC_0768948
PFAM domain coverage: 513 / 700 aa (73.3%)
1 aa700 aa
HptP2H-kinase_dimHATPase_cCheW
- Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
- Raw architecture: Hpt[3-104] | P2[164-240] | H-kinase_dim[312-373] | HATPase_c[422-559] | CheW[565-698]
- Domain count: 5
- Matched identifier: HKOC_0768948
- Positioned domains: Hpt 3-104 ; P2 164-240 ; H-kinase_dim 312-373 ; HATPase_c 422-559 ; CheW 565-698
Cluster members and taxonomy
Representative gene: GCF_000164175#HMPREF0220_RS08600
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283845
AssemblyASM2128384v1 · Contighaploid
Genome composition3 861 163 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 48 · RR 49CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key